ID A0A1H4VPB8_9ACTN Unreviewed; 818 AA.
AC A0A1H4VPB8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=SAMN04489844_3069 {ECO:0000313|EMBL:SEC82793.1};
OS Nocardioides exalbidus.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=402596 {ECO:0000313|EMBL:SEC82793.1, ECO:0000313|Proteomes:UP000198742};
RN [1] {ECO:0000313|Proteomes:UP000198742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22017 {ECO:0000313|Proteomes:UP000198742};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
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DR EMBL; FNRT01000002; SEC82793.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4VPB8; -.
DR STRING; 402596.SAMN04489844_3069; -.
DR Proteomes; UP000198742; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR30620:SF121; PERIPLASMIC BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 737..806
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 818 AA; 86664 MW; 254C37A112E1C064 CRC64;
MLPGERKVRY VTPALGQVPS GLGSSDPRET PMARTERRTL AVVASVGLTL ALATGALAAR
GLSDDEEALA PTRGRPSAGI ERKVDALLAR MTTKEKLQQV QLLSDGQITD ADAKAGVGSV
FSLVDAEKIN HFQRVAVEQS RLGIPILFAY DTVHGYRTVF PVPLGAASSF DPEVASADAE
VGARESAIQG IKQVYSPMVD VSHEPRWGRI VEGAGEDPYL GSVMGAARVK GAQGTDYSRP
DKVVSSVKHY VAYGEAEGGR DYNTTDLSES RLRNLYLPPF KAAIDAGADT VMCSFNSING
VPGCANKYTE TDILKKEWGF DGFIESDYTA VAELRACPPV TPDEGPCGHG VAADGPQAGA
AALMAGTDSE MVSTNIRDYG EQLLASRQIT MKRLDDAVRR ILRVKFRAGL FDHPYVDVAK
ASDPASYGKP ADLAKSRWAA GRSMVLLKND GGALPLDPAR STALIGPFGD TVDDVLGPWP
GRGADELAPA HVPLVEGLTA ASTGQVTYTQ ACNLAHNFDP PNVANPPLTP EDEVCAGPGD
DGTTIDDAVA AAEAADQVVL ALGENAYMSG EANARSELTL PGQQQKLLDA VAATGKPVVV
VLLNGRPLDL SAVQGKAAAI FEAWFPGTEG GHAVADVLFG TVNPGGKLPV TFPRRVGTAP
TYYNHEPTGR PCDAASKYNS RYRDLATCDP LYPFGFGLSY TTFEVGDLRL SRSSVRRDGR
LTASMRVTNT GSVAGDEVAQ LYLHDPVASL SQPVRRLRGF QRVSLDPGQS TTVTFTLDAS
DFGFYDNRGK YVVEPGLIEV YGGDSSTATM KATFTVTR
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