ID   A0A1H4WHG5_9ACTN        Unreviewed;       521 AA.
AC   A0A1H4WHG5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Bacterial peptide chain release factor 3 (BRF-3) {ECO:0000313|EMBL:SEC92772.1};
GN   ORFNames=SAMN04489844_3273 {ECO:0000313|EMBL:SEC92772.1};
OS   Nocardioides exalbidus.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=402596 {ECO:0000313|EMBL:SEC92772.1, ECO:0000313|Proteomes:UP000198742};
RN   [1] {ECO:0000313|Proteomes:UP000198742}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22017 {ECO:0000313|Proteomes:UP000198742};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. PrfC subfamily.
CC       {ECO:0000256|ARBA:ARBA00009978}.
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DR   EMBL; FNRT01000002; SEC92772.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4WHG5; -.
DR   STRING; 402596.SAMN04489844_3273; -.
DR   OrthoDB; 9801472at2; -.
DR   Proteomes; UP000198742; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0006415; P:translational termination; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.30.70.3280; Peptide chain release factor 3, domain III; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   InterPro; IPR035647; EFG_III/V.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR004548; PrfC.
DR   InterPro; IPR032090; RF3_C.
DR   InterPro; IPR038467; RF3_dom_3_sf.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   NCBIfam; TIGR00503; prfC; 1.
DR   NCBIfam; TIGR00231; small_GTP; 1.
DR   PANTHER; PTHR43556; PEPTIDE CHAIN RELEASE FACTOR RF3; 1.
DR   PANTHER; PTHR43556:SF2; PEPTIDE CHAIN RELEASE FACTOR RF3; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF16658; RF3_C; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF54980; EF-G C-terminal domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          5..271
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
SQ   SEQUENCE   521 AA;  56911 MW;  9665C9D4F96BAF2F CRC64;
     MPDTRPRRTF AVISHPDAGK STLTEALALH ARVITEAGAV HGKGDRRATV SDWMAMEKAR
     GISITSAALQ FVYRDHVINL VDTPGHSDFS EDTYRVLSAV DSAVMLVDAG KGLEPQTLKL
     FKVCALRGIP VLTVINKWDR PGLSALELMD LIQEKIKLRP TPLTWPVGEA GDFRGVLDRR
     TGEFVKYTRT AGGATRAPER RMAPDEVEDT DSHQWQAAAE EHELLTLDEA DHDQERFLAG
     ETTPVMFASA LQNFGVAQLL DLLLDIAPDP SATEGVDGSV RDTGDDFSAF VFKVQSGMNN
     AHRDRLAYAR VVSGHFERGM VVTHAGSGRP FATKFAQSVF GRDTAAVETA EPGDIIGFVN
     AQSLRVGDTV YVGDAIEYPP VPSFAPEHFV TASAGDISRY KQFRRGIEQL DQEGVVQVLR
     SDLRGDQNPV LAAVGPMQFE VVEDRMTNEF NSPIRLSRLD YQVARRTNAE GAAALAGMRG
     IEVLERSDGT HMALFVDQWR AMVTARDNPE IMLEALPAGG A
//