ID   A0A1H4WLR9_9ACTN        Unreviewed;       532 AA.
AC   A0A1H4WLR9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040298};
GN   ORFNames=SAMN04489844_3307 {ECO:0000313|EMBL:SEC94263.1};
OS   Nocardioides exalbidus.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=402596 {ECO:0000313|EMBL:SEC94263.1, ECO:0000313|Proteomes:UP000198742};
RN   [1] {ECO:0000313|Proteomes:UP000198742}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22017 {ECO:0000313|Proteomes:UP000198742};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable oxidoreductase that may play a role as regulator of
CC       mitochondrial function. {ECO:0000256|ARBA:ARBA00037217}.
CC   -!- SUBUNIT: Interacts with COX5B; this interaction may contribute to
CC       localize PYROXD2 to the inner face of the inner mitochondrial membrane.
CC       {ECO:0000256|ARBA:ARBA00038825}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC       {ECO:0000256|ARBA:ARBA00004305}.
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DR   EMBL; FNRT01000002; SEC94263.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4WLR9; -.
DR   STRING; 402596.SAMN04489844_3307; -.
DR   OrthoDB; 833207at2; -.
DR   Proteomes; UP000198742; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR10668:SF105; DEHYDROGENASE-RELATED; 1.
DR   PANTHER; PTHR10668; PHYTOENE DEHYDROGENASE; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
FT   DOMAIN          14..317
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   532 AA;  56277 MW;  CEFA9409C6C4DBB9 CRC64;
     MSWDAVVVGA GPNGLVAANR LLDAGWSVLL LEAQPTVGGA VRSDREVHPD FVHDTFSAFY
     PLAASSPTIA SFGLEDHGLE WCHAPSVLGH PLRDSSWAVL HRDRAKTAAG LDALHAGDGE
     SWLDLCAEWD RVGPHLIGAL LTPFPPVRSG VALLGALRHV GGLDMVRTLL TPVADLTRER
     FGGEAARVLL AGNAGHADIP LDAPGSGLMG LLLAMMGQTV GFPVPRGGAG ELTGSLARRF
     TANGGTIRTD AEVTEIRVRN GRAHTVVTAD GEGHRALRAV VADVLAPALY TRLLDPSAVP
     DRVLRSLRRF ELDPGTVKVD WALADEVPWT DGPALRSGTV HIADDVDDMG LALSQVGSGV
     VPARPFMLTG QMTTADPDRS PAGTESFWAY SHVPQRTRHD AGDGGITGTW DRDDCERYAD
     RMQARLEEVA PGFGARVLAR RVLGPRELEE RDANLAGGAL NGGTAQLHQQ LVFRPVPGLG
     RAETPVRGLY LGSASAHPGG GVHGACGDNA ARAAIAHDRV DRWVPWRSSR PV
//