ID A0A1H4XLF7_9ACTN Unreviewed; 240 AA.
AC A0A1H4XLF7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases {ECO:0000313|EMBL:SED05554.1};
GN ORFNames=SAMN05216482_5772 {ECO:0000313|EMBL:SED05554.1};
OS Streptomyces sp. PAN_FS17.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1855351 {ECO:0000313|EMBL:SED05554.1, ECO:0000313|Proteomes:UP000199275};
RN [1] {ECO:0000313|Proteomes:UP000199275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAN_FS17 {ECO:0000313|Proteomes:UP000199275};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNTN01000001; SED05554.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4XLF7; -.
DR STRING; 1855351.SAMN05216482_5772; -.
DR OrthoDB; 41390at2; -.
DR Proteomes; UP000199275; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567:SF79; CAMP-ACTIVATED GLOBAL TRANSCRIPTIONAL REGULATOR CRP; 1.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SED05554.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199275};
KW Transferase {ECO:0000313|EMBL:SED05554.1}.
FT DOMAIN 10..114
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 145..229
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 240 AA; 25468 MW; 5B70947C56B9E40D CRC64;
MGLLGNELAF AQTLTPQEHE GVMALGHHKR YPADAHLLTE GDRSSHVVII IRGWVTVSVA
TDRGATRLIL GLRGPGELLG EMAALDQHPR SATVRALGPI EAQVISGDAF RRFLALHPRV
SGLVIRQLTF RLRSADQERS ALASLTVLQR LAGRLIELSG ADTSGPYAPS AAAPSSGTAV
SGPVVQLAQD ELAATIGATR EAVAKALRLL RTQNIVRTGN RMVEILDPAL LALLADGHQE
//
