ID   A0A1H5AWM4_9ACTN        Unreviewed;       308 AA.
AC   A0A1H5AWM4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Bifunctional non-homologous end joining protein LigD {ECO:0000313|EMBL:SED46030.1};
GN   ORFNames=SAMN05216482_7514 {ECO:0000313|EMBL:SED46030.1};
OS   Streptomyces sp. PAN_FS17.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1855351 {ECO:0000313|EMBL:SED46030.1, ECO:0000313|Proteomes:UP000199275};
RN   [1] {ECO:0000313|Proteomes:UP000199275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PAN_FS17 {ECO:0000313|Proteomes:UP000199275};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNTN01000001; SED46030.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5AWM4; -.
DR   STRING; 1855351.SAMN05216482_7514; -.
DR   OrthoDB; 4296267at2; -.
DR   Proteomes; UP000199275; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02778; ligD_pol; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199275}.
FT   DOMAIN          36..286
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
SQ   SEQUENCE   308 AA;  34447 MW;  D9DB6D2A03843B32 CRC64;
     MTDGGTRRVR AGRRTVEVKR VDKVLFPGSG DAKEYTKGDL VDYHRSVARY MLPHLRSRPL
     MLERHPDGLD GPEFMQKNTP EHYPDWITRA EVSKEDGTVR HTICDDTATL LYLTDQACLT
     MHRWLSRTSS INCPDRLVFD LDPAGDDFGQ VREAAGFLGE LLDELELPSA PMTTGSRGLH
     IVVPLTGRQD FDEVREFARD VADTLAAAHP DRLTTAARKK ERGDRLYLDV QRNAYAQTVV
     APYTVRARPG APVATPIAWA DLDDPDLHAR RWTIADAVEK ARSDPWAGLM GRGRALGPAR
     RRLDALKG
//