ID   A0A1H5BQ23_9MICO        Unreviewed;       343 AA.
AC   A0A1H5BQ23;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Ketopantoate reductase {ECO:0000313|EMBL:SED56378.1};
GN   ORFNames=SAMN04488554_0160 {ECO:0000313|EMBL:SED56378.1};
OS   Ruania alba.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Ruaniaceae; Ruania.
OX   NCBI_TaxID=648782 {ECO:0000313|EMBL:SED56378.1, ECO:0000313|Proteomes:UP000199220};
RN   [1] {ECO:0000313|Proteomes:UP000199220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21368 {ECO:0000313|Proteomes:UP000199220};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNTX01000001; SED56378.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5BQ23; -.
DR   STRING; 648782.SAMN04488554_0160; -.
DR   OrthoDB; 9796561at2; -.
DR   Proteomes; UP000199220; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR013752; KPA_reductase.
DR   InterPro; IPR013332; KPR_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR21708:SF26; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR   PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF08546; ApbA_C; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199220}.
FT   DOMAIN          4..162
FT                   /note="Ketopantoate reductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02558"
FT   DOMAIN          188..308
FT                   /note="Ketopantoate reductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08546"
SQ   SEQUENCE   343 AA;  35501 MW;  91536D8D64DF7416 CRC64;
     MRYIVIGAGG VGGTIGGRLH ATGHDVVLVA RGAHGRALAA DGLTLLTPDG PGTHQIPVVS
     HPDELAGGLR PGDALVLAVK GQDTAAALDV WADVPVASGG TAAERLPLFL AQNGVANEPF
     AARVFDDVHG VCVWLPATHL EPGVVVAEGT PVHGVLHLGR WPGGVDDVDR QVATDLEAAG
     FAAPLREDVM RWKYAKLLGN LGNAVEALTG TGSDEARSML TDVRAEGEAA LAAAGIMAAT
     PQEEAELRPT MRVGEVPGHT RLGGSSWQSL RRGTGSIEAD YLNGEIAMLG RRHGVPTPLN
     DTLTRWARRA ARTGQEPGSC TVEEVRRAAE AVPVTDGVDA PAH
//