ID A0A1H5C471_9ACTN Unreviewed; 900 AA.
AC A0A1H5C471;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Transcriptional regulatory protein, C terminal {ECO:0000313|EMBL:SED61643.1};
GN ORFNames=SAMN05216482_8165 {ECO:0000313|EMBL:SED61643.1};
OS Streptomyces sp. PAN_FS17.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1855351 {ECO:0000313|EMBL:SED61643.1, ECO:0000313|Proteomes:UP000199275};
RN [1] {ECO:0000313|Proteomes:UP000199275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAN_FS17 {ECO:0000313|Proteomes:UP000199275};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; FNTN01000001; SED61643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H5C471; -.
DR STRING; 1855351.SAMN05216482_8165; -.
DR OrthoDB; 4336084at2; -.
DR Proteomes; UP000199275; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000199275};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..98
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..98
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 274..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 900 AA; 94601 MW; A286003E14314D1A CRC64;
MKFQVLGPLT VLGDGGPVAL SGVKQRATLG HLLLHANEVV ATSALMRALW AGEPPPTARK
MLQNAVSALR GLLAAGDTED AHGGPVLLTH APGYLLRVDG DDLDLTAYRA LADRGRADLA
AGAWSAAAPT LRAALDLWRG PVLADLAESG TDWPELRTLA QARTATREDL YEAELACGRH
DDVLEELRTH AEREPERERL CAQLMLALYR RGHQSDALDA YRRTRTALAS RLGLEPGRVL
RAVERAVLDH DPVLGQPDAL AIMALDGEPR RLLPTAGSPG PAAVPPASAV GFDSLPAPRP
PAPPALPAPP RAAFPYPAAP AGVLTEQHKQ LSMLLVRTTL GKGLGGDPED AARLSGELAV
AIRDEVARHG GKVSGVLGPV TFALFGVVRT REDDAERAVR AGRAILRRLR QYGAGGPVPV
HGGAAPRVAV ATGDVVVTCA ADGTGAVPIV NGAVPQSCAD LLRTVPPGGI RVCATTRSGT
ERSLVYGPAG PDGAAEPLGT RTTRTHTPPA LVGRDREMAQ LGGALDDVAR RQRPCLLTAL
GEPGAGKTRL MAELARLARR SPHGYRVVTG HSSWCDRDRP LALLDRTLAS ASASATGTGT
GTDERANDAL ARTVHALFGT GDRGTWLLDR LGPLLRAEPP APADWPDLAT AWRLLLTGLA
AERPLLLVLE DLHSAPDPVL DLVTELADAA GPVPLLLAVT ARPELLDRRP TWGGGRRDAL
ALTLDPLDEP SSAALLDALL AGALPADLRR DVLARVGGNP LYAVEYAREL AAAGHGGPAG
PPSMPRHVRQ VVAAHLDTLP PLAKAVLVCA SALGGVCCAD GVAAVGGVDR TEAAHWLDHL
ERRDFLRRSR HPSATGALRY AFRHPATREA VDALVPRTVR EDRRRRAEAW AESTAAQLTV
//
