ID A0A1H5C618_9ACTN Unreviewed; 351 AA.
AC A0A1H5C618;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:SED62076.1};
GN ORFNames=SAMN05216489_03942 {ECO:0000313|EMBL:SED62076.1};
OS Streptomyces sp. 3213.3.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1855348 {ECO:0000313|EMBL:SED62076.1, ECO:0000313|Proteomes:UP000198754};
RN [1] {ECO:0000313|EMBL:SED62076.1, ECO:0000313|Proteomes:UP000198754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3213 {ECO:0000313|EMBL:SED62076.1,
RC ECO:0000313|Proteomes:UP000198754};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNTK01000001; SED62076.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H5C618; -.
DR STRING; 1855348.SAMN05216489_03942; -.
DR Proteomes; UP000198754; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000198754};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..68
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 351 AA; 37695 MW; 716F441122407C49 CRC64;
MASHGARGRS GGRPTLEEVA ARAGVGRGTV SRVINGSPRV SDATRAAVEA AVAELGYVPN
TAARALAANR TDAIALVVPE PETRFFAEPY FSDMLKGVGA ELSETEMQLL LIFAGSDRER
QRLAQYLAAH RVDGVLLVSV HADDPLPDLL AQLEIPAVIS GPRSAAETLT SVDSDNYGGA
RSAVEHLMSR GRTRIAHITG RLDVYGAQRR VDGYREALLD AGHEVDEHLI QPGDFTEEGG
RRAMKELLAR RPDVDAVFAG SDVMAAGARQ VLREEGRVIP DDVALVGYDD SAIARHMDPP
LTSVRQPIEE MGRAMIDLLL AEIADRRPAT SRGLERRQAV LATELVTRAS S
//
