ID   A0A1H5CBV8_9ACTN        Unreviewed;       762 AA.
AC   A0A1H5CBV8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Type IV secretion-system coupling protein DNA-binding domain-containing protein {ECO:0000313|EMBL:SED64136.1};
GN   ORFNames=SAMN05216489_03992 {ECO:0000313|EMBL:SED64136.1};
OS   Streptomyces sp. 3213.3.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1855348 {ECO:0000313|EMBL:SED64136.1, ECO:0000313|Proteomes:UP000198754};
RN   [1] {ECO:0000313|EMBL:SED64136.1, ECO:0000313|Proteomes:UP000198754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3213 {ECO:0000313|EMBL:SED64136.1,
RC   ECO:0000313|Proteomes:UP000198754};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNTK01000001; SED64136.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5CBV8; -.
DR   STRING; 1855348.SAMN05216489_03992; -.
DR   Proteomes; UP000198754; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR019476; T4SS_TraD_DNA-bd.
DR   PANTHER; PTHR30121:SF6; TYPE IV SECRETION SYSTEM PROTEIN CAGE; 1.
DR   PANTHER; PTHR30121; UNCHARACTERIZED PROTEIN YJGR-RELATED; 1.
DR   Pfam; PF10412; TrwB_AAD_bind; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000313|EMBL:SED64136.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198754};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          348..676
FT                   /note="Type IV secretion system coupling protein TraD DNA-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF10412"
FT   REGION          703..762
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        727..751
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   762 AA;  82383 MW;  5D5F54E27B491238 CRC64;
     MSDTTRLVAS AALFSATIAI ILILRFRDQL TRDTARVTYR LGFPRDLTIG QVTAFLHALT
     RLRPSRGWLF GRDSVVFESV GRPGRIEHRL RLPEHQADVL LRQLRGIVPN LRTTLIDSPA
     LPPARWLRRI RLTTTARPLR TDAPEAFTTG VLSALQPLAR DEALIYQLVV YPVRTPQLPL
     ARRRTSGSGL VPPWLQTLSQ WLTATPPATL DKQAAADFKA KTAEPWFAVI GTVGAAASDR
     PQAHLLVGRL MASLHLLDQN GAALVPRWLP QRAADWLARG AAGNTAAPIY VNAREAATML
     GWPLAGPTMP GLALTGGRSF PPVPELPSYG RILGTATYDG LQRTIAMSAA DGLMHQLVTG
     PTGSGKSTLL LNQLTQDIQA GRGVILLDPG GDLARDVADR IPEARISDLI YLDASDDRPV
     GINPLACSKD DAELVADQVM ELIKANADSW GPRLEEVLKA ALVLLAATPG MTLVELPAVL
     TDEVFRASLL SRLDSAFAPT VGAFFARFNS WSEGERGQAV SAVINKISPL TDRRQLRAML
     GQAKPAWTMQ EVMEQRKILL VALPSGLAGS YAVDLLGGLL VSMVWNAAMR RAAVTRDQRH
     PTFLYIDEAA RFLRSGADLT DMLARARGHF LGIIAALQHI TQVPPNLRAA LLSEARTKVV
     LQPGADDAAT LARALGPQVK PEDLLTLEPR TAVAVIVTNG RVNPPVSIAT NPPPEPTGFG
     DQARAASRAA YDRDRAEVEQ EITDRRQASR PRSSARGARP AQ
//