ID   A0A1H5DFS2_9ACTN        Unreviewed;       323 AA.
AC   A0A1H5DFS2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Threonine dehydratase {ECO:0000313|EMBL:SED77679.1};
GN   ORFNames=SAMN05216533_0523 {ECO:0000313|EMBL:SED77679.1};
OS   Streptomyces sp. Ag109_O5-10.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1855349 {ECO:0000313|EMBL:SED77679.1, ECO:0000313|Proteomes:UP000198812};
RN   [1] {ECO:0000313|EMBL:SED77679.1, ECO:0000313|Proteomes:UP000198812}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ag109_O5-10 {ECO:0000313|EMBL:SED77679.1,
RC   ECO:0000313|Proteomes:UP000198812};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR   EMBL; FNTQ01000001; SED77679.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5DFS2; -.
DR   STRING; 1855349.SAMN05216533_0523; -.
DR   Proteomes; UP000198812; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR   CDD; cd01562; Thr-dehyd; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   4: Predicted;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198812}.
FT   DOMAIN          18..305
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   323 AA;  32829 MW;  22C84A9E7D898164 CRC64;
     MNGIIGIADL EAAARVVEGH VVRTPTVPSP GLSELLGVPV TAKLELLQRT GSFKARGAAA
     KLLSLSEAER AAGVVAVSGG NHGIALAVMA AALDVKATVV MPRTAPARSI RLAEAAGASV
     RLTDGMDSAF ELVPRLRDEG LTLVHPFDDP VVIAGQGTVG LELAEDADGD LTDVIVSVGG
     GGLIAGVAAA LRARRPAVRV WGVETAGAQA MSEALAAGGP LPVAVSSIVT TLSAPSVSRL
     TYDHAVALVE EVLVVPDREA VRGSLEFAEH AKVWTEPAAG CLLPAARQVL DRVGGGARIG
     LVVCGGNVTH QEIAGWTERF GLD
//