ID   A0A1H5DS19_9PSEU        Unreviewed;       221 AA.
AC   A0A1H5DS19;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Phosphate-specific transport system accessory protein PhoU {ECO:0000256|PIRNR:PIRNR003107};
GN   ORFNames=SAMN04489727_9547 {ECO:0000313|EMBL:SED81576.1};
OS   Amycolatopsis tolypomycina.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=208445 {ECO:0000313|EMBL:SED81576.1, ECO:0000313|Proteomes:UP000199622};
RN   [1] {ECO:0000313|EMBL:SED81576.1, ECO:0000313|Proteomes:UP000199622}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44544 {ECO:0000313|EMBL:SED81576.1,
RC   ECO:0000313|Proteomes:UP000199622};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in the regulation of phosphate uptake.
CC       {ECO:0000256|PIRNR:PIRNR003107}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|PIRNR:PIRNR003107}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR003107}.
CC   -!- SIMILARITY: Belongs to the PhoU family.
CC       {ECO:0000256|PIRNR:PIRNR003107}.
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DR   EMBL; FNSO01000004; SED81576.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5DS19; -.
DR   STRING; 208445.SAMN04489727_9547; -.
DR   OrthoDB; 9814256at2; -.
DR   Proteomes; UP000199622; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030643; P:intracellular phosphate ion homeostasis; IEA:InterPro.
DR   GO; GO:0045936; P:negative regulation of phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR028366; P_transport_PhoU.
DR   InterPro; IPR038078; PhoU-like_sf.
DR   InterPro; IPR026022; PhoU_dom.
DR   NCBIfam; TIGR02135; phoU_full; 1.
DR   PANTHER; PTHR42930; PHOSPHATE-SPECIFIC TRANSPORT SYSTEM ACCESSORY PROTEIN PHOU; 1.
DR   PANTHER; PTHR42930:SF3; PHOSPHATE-SPECIFIC TRANSPORT SYSTEM ACCESSORY PROTEIN PHOU; 1.
DR   Pfam; PF01895; PhoU; 2.
DR   PIRSF; PIRSF003107; PhoU; 1.
DR   SUPFAM; SSF109755; PhoU-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR003107};
KW   Phosphate transport {ECO:0000256|PIRNR:PIRNR003107};
KW   Transport {ECO:0000256|PIRNR:PIRNR003107}.
FT   DOMAIN          18..103
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
FT   DOMAIN          122..203
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
SQ   SEQUENCE   221 AA;  24425 MW;  9E09B22308699F0D CRC64;
     MREAYHVELE QLADHLAAMS VQVADAMERA TRALLEVDLG LAEQVISDDA KVDDARAQCE
     EQAYALLALQ APVATDLRTV LAAIHAAESL ERMGDLALHV AKAARRRHPE PVLPDAVRPY
     FAEMGEVAVK LARQTEQVIK SKDVEAAKTL ESDDDQVDDI HRHLFTVIMD REWPHGVAAA
     VDVTLLGRFY ERYADHAVSV AKRMIFVVTG KMPGYGSDDD I
//