ID A0A1H5H8V5_9ACTN Unreviewed; 490 AA.
AC A0A1H5H8V5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SEE24184.1};
GN ORFNames=SAMN05216533_1765 {ECO:0000313|EMBL:SEE24184.1};
OS Streptomyces sp. Ag109_O5-10.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1855349 {ECO:0000313|EMBL:SEE24184.1, ECO:0000313|Proteomes:UP000198812};
RN [1] {ECO:0000313|EMBL:SEE24184.1, ECO:0000313|Proteomes:UP000198812}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ag109_O5-10 {ECO:0000313|EMBL:SEE24184.1,
RC ECO:0000313|Proteomes:UP000198812};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNTQ01000001; SEE24184.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H5H8V5; -.
DR STRING; 1855349.SAMN05216533_1765; -.
DR OrthoDB; 5241729at2; -.
DR Proteomes; UP000198812; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR007891; CHASE3.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF05227; CHASE3; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SEE24184.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000198812};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 218..270
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 490 AA; 52417 MW; 1DFE736CE9398E8F CRC64;
MHLLASRTRR TGGVRGVVRR LIVASSLLVL PIGIAFAILL HSAVDLRAVH QLAQNSEEVR
IVANQEEQQV LAFDTDLHGY ALTGQPQYVK RWQNSVAAFP KEADKLKSLT AHSPGELARA
EWIQNMCSAY IKDSSTSLAN ATGHGLSPRE RSVLNGEDNR RFQVILDGLH DLVAGEQTMA
KEREAHAATP TDQAVAATIA GLTGFVVTTI GVAGYVIRAI VRPVRRTAAM ADQLANGDLT
ARTPETAIGE IGLLERSFNR MADSLEQGHA ELSTSRARIL AATDRARRSI ERDLHDGTQQ
RLVALLLEMQ VAQSTVPAEQ QELRARISRA ADSLKGVLDD LHELSRGIHP AVLTHGGLAA
ALRALARRSP VPVELDVDVP RGLPEPVEVA AYYVVSEALT NTSKHAHASC VHVCARTGQG
VLRLSVRDDG VGGADTGTGS GLVGLTDRVR ALGGMFDLHS PKGRGTTLRA HLPLVAPATV
AGERNRAPLS
//
