ID   A0A1H5HL36_9ACTN        Unreviewed;       391 AA.
AC   A0A1H5HL36;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Threonine dehydrogenase {ECO:0000313|EMBL:SEE28736.1};
GN   ORFNames=SAMN05216533_1875 {ECO:0000313|EMBL:SEE28736.1};
OS   Streptomyces sp. Ag109_O5-10.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1855349 {ECO:0000313|EMBL:SEE28736.1, ECO:0000313|Proteomes:UP000198812};
RN   [1] {ECO:0000313|EMBL:SEE28736.1, ECO:0000313|Proteomes:UP000198812}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ag109_O5-10 {ECO:0000313|EMBL:SEE28736.1,
RC   ECO:0000313|Proteomes:UP000198812};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR   EMBL; FNTQ01000001; SEE28736.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5HL36; -.
DR   STRING; 1855349.SAMN05216533_1875; -.
DR   OrthoDB; 241504at2; -.
DR   Proteomes; UP000198812; Unassembled WGS sequence.
DR   CDD; cd08282; PFDH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198812}.
FT   DOMAIN          27..137
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          188..257
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   391 AA;  42047 MW;  6B9983E8A64737B1 CRC64;
     MRAAVYEGPR TVAVKDVPDA RIEHPCDIIV KITTTNICGS DLHMYEGRTS FESGRTLGHE
     NLGQVVEVGS AVRKVQVGEY VVLPFNIACG FCKQCERGLT NYCLTMQPEP ALAGAAYGFA
     DMGPYQGGQA ELLRVPYGDF NALRLGEDAA ERQTDYVMLA DIFPTGYHAT EMAHVKPGDQ
     TVVFGAGPVG LMATYSALLR GAGRVWTVDH QPDRLRKAEE IGAIAINTAE QDPAEVVKEA
     TLGLGADNGC ECVGYQAHDP QGHEDASLTL NGLIDSVRFT GDIGVVGVFL PQDPGGAEAQ
     GELEAQGKVP IDFGMMWFKG QHMGTGQAPV KRYNRALRDL IAGGKAKPSF VVSHELGLDE
     APTAYEHFDA RDEGWTKVVL HPNGHGNGHK R
//