ID A0A1H5HW13_9FLAO Unreviewed; 531 AA.
AC A0A1H5HW13;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=SAMN04488034_101262 {ECO:0000313|EMBL:SEE32193.1};
OS Salinimicrobium catena.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Salinimicrobium.
OX NCBI_TaxID=390640 {ECO:0000313|EMBL:SEE32193.1, ECO:0000313|Proteomes:UP000199448};
RN [1] {ECO:0000313|EMBL:SEE32193.1, ECO:0000313|Proteomes:UP000199448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23553 {ECO:0000313|EMBL:SEE32193.1,
RC ECO:0000313|Proteomes:UP000199448};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR EMBL; FNUG01000001; SEE32193.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H5HW13; -.
DR STRING; 390640.SAMN04488034_101262; -.
DR OrthoDB; 9767858at2; -.
DR Proteomes; UP000199448; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:SEE32193.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199448}.
FT DOMAIN 303..435
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 531 AA; 61478 MW; DE731DCF82F1DC8F CRC64;
MEEFAALIKE LDSTNKTTVK VAALTRYFQR VPGKDKVWAI AILSHRRPPR PVNTTLLRTF
AAELAQIPLW LFEESYHIVG DLAETIALVI PPSEENSEKS LSQYLDEIID LKAATESEKK
EYLHENWLAL NYYERFVFTK LITGSFRIGV SQKLMTRALS KATDIDEDVL AYKLMGDWDP
QKISFEKLIL EENEEDYLSK PYPFYLAYAI EGEPGDLGDP AEWSAEHKWD GIRAQVVVRN
GEVFVWSRGE ELVTDKYPEF SDFTKVLPDG TVLDGEILPF PEGEIGTFND LQTRIGRKNV
SKALLKKTPV ILKAYDLLEW QGEDLRKKPF SERREILEEL HSKVGHEELP LHLSHTISFE
RWEEAVAERE RAREVRSEGL MLKRWDSPYL VGRKKGDWWK WKVEPLTIDA VLTYAMRGHG
RRSNLFTDYT FGLWDEEKEE LVTFAKAYSG LTDAEFRQVD AFIKKNTLER FGPVRSVKPE
LVFEIAFEGI AESNRHKSGV ATRFPRILRW RQDKKIEEAN TLEDLKALIP K
//
