ID A0A1H5IRR4_9FLAO Unreviewed; 1590 AA.
AC A0A1H5IRR4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN04487765_2531 {ECO:0000313|EMBL:SEE42767.1};
OS Tenacibaculum sp. MAR_2010_89.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Tenacibaculum.
OX NCBI_TaxID=1250198 {ECO:0000313|EMBL:SEE42767.1, ECO:0000313|Proteomes:UP000198792};
RN [1] {ECO:0000313|EMBL:SEE42767.1, ECO:0000313|Proteomes:UP000198792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mar_2010_89 {ECO:0000313|EMBL:SEE42767.1,
RC ECO:0000313|Proteomes:UP000198792};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; FNUB01000005; SEE42767.1; -; Genomic_DNA.
DR STRING; 1250198.SAMN04487765_2531; -.
DR Proteomes; UP000198792; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 2.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 4.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 3.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198792};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 811..1270
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1277..1589
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1590 AA; 176702 MW; EDE001F9692C7DD8 CRC64;
MNSIAPSEII IKGAKTNNLK NISLRIPHNK FIVVSGVSGS GKSSLISEII AKEGQRRYFE
TLPSFARQFL GKLKRPDVDE IEGLSPVIFI GQQTAGMHAR STVGTISDIY DLLRLLFART
GIGTENVVLS RALFSFNSEV GKCKRCNGIG KEEQIDLNSL ITFPKRTIRE GALAPTLPNG
YIMYSQVTID VLNHVCNSEG FNVDIPWNEL TKKQQDVILY GSTKIKVPFG KHSLESRLKW
TGIKAKPREE GYYKGMIPIM SDILKRDRNA NILKYVHAVI CEDCNGNRLN KTALNVCVHG
KSIAEIVTLE LTKLKSWIKT NSWGDIATEI IKKIESQVSL LEDLGLGHLT IDRSSFSLRS
SEIQRIRVAN QILTPLSNVL YIFDEPSIGL HKEENEKLIY HFKQLVKKGN TVIVVEHNLN
TITNADHIIE VGPKAGINGG ELVFNGSFLE FIKQKTLKDV SPTFRAINKN YLQLDSKKKT
STDFIHLIGC YERNLKDIDV KFQLGKLNVV SGKSGSGKAS LVKETLIKVI EGKLGNKSQK
LPKLESYKNI DSIDKLVYID HTPIGKTPRS NPATYLGLSD HIRDIYAKQP ESKLLGFTKS
RFSFNNKGGR CEVCQGAGKT QIGMHFLGTI DLICGTCNGD RFNKETLQVT YNGLSIADIY
RLSVNDALKF FEGHKKITQG LETLKEIGLG YLTLGHSSTT LSGGEAQRIK IANQLQKKDT
GNTLYVIIEP SIGLHQDDIE SLLNLFKAIQ NKGNTIVCVE QNQTIISVSD WHIELGPIGG
VNGGNILHQG IPNRNEESRY NTINNQIEET VISNDIVLKG VTTNGLKNID VRIPKNQLTV
VTGVSGSGKS SLVYDTLFAE SNARFTESLS TYNRSFLKQN SNAELESFSG LGPAIGVNRR
GGTTTKRSTV GTLSGIHDAF RLLYSRIAQY EEKIYTAQHF SFNHHLGACP SCEGIGVKLK
CNPDEIIIFP EKSIFEGAIS TNKAIAYYSD VNGQFMAILN EVAKQNKWNL QLPWEDLDAE
IKNVILYGTG EEVWSLTWNF KTKSRSGTQE LNAKWLGLCN YIDSEYQRKI HNKNKKNLED
LLHEVECYTC KGSRLKNELL HVKFQGKNIY EISKQNIVSC YELIESIPSN LDKVILEISK
VVLPAVKKSL RTIIDLGLGY LSLDRSVTTL SGGERQRITL AGQLSSHLYG VTYVLDEPTI
GLDDKQVTVL SKVLKKIVAN GNTVVVVEHD ISFIKKTDYI IEMGPGAGRF GGEIIYQGKI
NGINKVKQSI TRRLFELDEN IIEKVFNEKG KPFEIKGAFA NNLKKIDVKF YSGQVIALTG
VSGSGKSSLV KEVLFNSWLK KKPVNCYSLH GLNQFEDVLL IDQEILVQNR LGTPVVYTGI
IESLKKIYSS TELAKKEGVK KADFSYQSKK GKCETCAGHG KVKTSMDFMS DIWLLCDTCK
GLRYNDAILA CKYKEHSIGE VLKMTVVEAI DFFKTEEIIL KQLHILKKVG VGHIVLGQSG
NTLSGGESQR LKLGVSMMQK KKVKTLYLFD EPSTGLHYFD NLQLISVFQS LINNGDTVLF
IEHNKTLINS ADKVIKLGPG SGEKGGIVID
//
