ID   A0A1H5KN61_9FLAO        Unreviewed;       929 AA.
AC   A0A1H5KN61;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE   AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN   ORFNames=SAMN04487765_3660 {ECO:0000313|EMBL:SEE66120.1};
OS   Tenacibaculum sp. MAR_2010_89.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Tenacibaculum.
OX   NCBI_TaxID=1250198 {ECO:0000313|EMBL:SEE66120.1, ECO:0000313|Proteomes:UP000198792};
RN   [1] {ECO:0000313|EMBL:SEE66120.1, ECO:0000313|Proteomes:UP000198792}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mar_2010_89 {ECO:0000313|EMBL:SEE66120.1,
RC   ECO:0000313|Proteomes:UP000198792};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC       {ECO:0000256|ARBA:ARBA00038000}.
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DR   EMBL; FNUB01000005; SEE66120.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5KN61; -.
DR   STRING; 1250198.SAMN04487765_3660; -.
DR   Proteomes; UP000198792; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR   Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR004602; UvrA.
DR   InterPro; IPR041552; UvrA_DNA-bd.
DR   InterPro; IPR041102; UvrA_inter.
DR   NCBIfam; TIGR00630; uvra; 1.
DR   PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR   PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR   Pfam; PF13304; AAA_21; 1.
DR   Pfam; PF17755; UvrA_DNA-bind; 1.
DR   Pfam; PF17760; UvrA_inter; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198792};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          245..581
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   DOMAIN          588..925
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
SQ   SEQUENCE   929 AA;  104873 MW;  D87662B1EA5BA75E CRC64;
     MKRDLSTINP KENIIIKGAK LHNLKDIDVV IPRNKLVVIT GLSGSGKSSL AFDTLYAEGQ
     RRYVESLSSY ARQFLGKLHK PKVDYIKGIS PAIAIEQKVN STNPRSTVGT STEIYDYIKL
     LYARIGKTFS PVSGKEVKKH TVTDVLNFIK KFEERSKLLL LAPITISKDR KIETVLQVLM
     QQGYARLKYN NEVYRIDDFP IKTFKGNDFF LVIDRVVVKH EEDFYNRLAD AIQTAFFEGK
     GICFVDDMST NETTSFSNKF ELDGITFLEP NTHFFSFNNP YGACPTCEGY GNVIGIDEEL
     VIPNTGLSIY EDAIFAFKTD SYKKYKEALI LNAADFNIPI HKPWFELTDE QKELVWNGTS
     KFNGIHHLFK TLEEKSYKIQ NRVMLSRYRG KTTCTECNGK RLRKETNYVK VYNKTISELV
     SLPLDELASF FSTIKLNKYE EKIGKRLLTE INNRLQFLQD VGLNYLTLNR TSNTLSGGES
     QRINLATSLG SSLVGSMYIL DEPSIGLHPK DTERLIKVLK NLRDLGNTVI VVEHDEDIMK
     EADYIIDIGP EAGTFGGNVV AEGTYKELLN SNSLTAQYLS EKLTIEIPKK RRVSKNTIDI
     IGARENNLKN IDVSFPLNNL TVITGVSGSG KSTLVKKILY PAMQKKLIGY GNKLGQHTEV
     KGSFETLKHI EFIDQNPIGR SSRSNPVTYI KAYDDIRKLL SSQKLSKIRN YQPKHFSFNV
     EGGRCEVCKG EGEVTIEMQF MADVHLQCEA CNGKRFKKEV LEVTFEEKNI DDILNLTIDD
     AVSFFTEFNQ PKIARKLKPL QDVGLGYVQL GQSSSTLSGG EAQRIKLASF LVKGTTKDKA
     LFIFDEPTTG LHFHDIKKLL NSFNALIERG HSIIVIEHNI ELIKCADYII DLGLEGGKNG
     GNLIFSGTPE ELVKNKKSYT SKYLKEKII
//