ID A0A1H5NAP6_9ACTN Unreviewed; 530 AA.
AC A0A1H5NAP6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=IclR family transcriptional regulator, pca regulon regulatory protein {ECO:0000313|EMBL:SEE98702.1};
GN ORFNames=SAMN05216533_4932 {ECO:0000313|EMBL:SEE98702.1};
OS Streptomyces sp. Ag109_O5-10.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1855349 {ECO:0000313|EMBL:SEE98702.1, ECO:0000313|Proteomes:UP000198812};
RN [1] {ECO:0000313|EMBL:SEE98702.1, ECO:0000313|Proteomes:UP000198812}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ag109_O5-10 {ECO:0000313|EMBL:SEE98702.1,
RC ECO:0000313|Proteomes:UP000198812};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNTQ01000001; SEE98702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H5NAP6; -.
DR STRING; 1855349.SAMN05216533_4932; -.
DR OrthoDB; 9807558at2; -.
DR Proteomes; UP000198812; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF34; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 2.
DR Pfam; PF01614; IclR; 2.
DR SMART; SM00346; HTH_ICLR; 2.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51077; HTH_ICLR; 2.
DR PROSITE; PS51078; ICLR_ED; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198812};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 19..86
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 80..272
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT DOMAIN 303..363
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 364..520
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT REGION 177..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 55723 MW; 203F66FA75255622 CRC64;
MTVPLPSVPE AHEPPAEAVA PLIRGVAVLA ALTEAGGTLS ASALERRTGL ARSTVDRITA
TLARMGYVRQ DGRDAVLTPR VMELGNAYLA ALRLPALLDG HADAVADELD ESVSLAVPDR
DGIRFIHQAT RRRAMSVSFR IGDLLPAERT APGPLFAAEW TEREWAAWRA RRAADPADAG
FPAVPPRNPA ADDDFEARTE EARHTGWALD DQLIEPGLVA VSVPVRDPGT GRVACVASVV
SHTSRHTAAD LRETLLPRLR TAVTAMEAEL RAAGARPAEP GPPPAGLAVW TTASKHELGR
DFVESLARGL TVLTAFGEGR SALTLTDVAK ATGLARATAR RALITYEHLG LVAADGRAFA
LTPRVLSLGY PPLSRTTLSR LAAPRLRALA DLLDEPTALA VPVPGDPGTG PAEIQYVAVA
AASRVLTVDI TVGTRLPAGR TALGRALLGL AGADGYALAD EELESGLRSI AVPVRDRAGR
PVAAVNVATH AARRTLAECV TEVLPALHDT AARIQDDLHI ASRFTQVPLS
//
