ID   A0A1H5PSN5_9ACTN        Unreviewed;       771 AA.
AC   A0A1H5PSN5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=HAD-superfamily subfamily IB hydrolase, TIGR01490 {ECO:0000313|EMBL:SEF16872.1};
GN   ORFNames=SAMN05216533_8029 {ECO:0000313|EMBL:SEF16872.1};
OS   Streptomyces sp. Ag109_O5-10.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1855349 {ECO:0000313|EMBL:SEF16872.1, ECO:0000313|Proteomes:UP000198812};
RN   [1] {ECO:0000313|EMBL:SEF16872.1, ECO:0000313|Proteomes:UP000198812}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ag109_O5-10 {ECO:0000313|EMBL:SEF16872.1,
RC   ECO:0000313|Proteomes:UP000198812};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNTQ01000001; SEF16872.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5PSN5; -.
DR   STRING; 1855349.SAMN05216533_8029; -.
DR   OrthoDB; 25607at2; -.
DR   Proteomes; UP000198812; Unassembled WGS sequence.
DR   GO; GO:0080019; F:alcohol-forming very long-chain fatty acyl-CoA reductase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 1.20.1440.100; SG protein - dephosphorylation function; 1.
DR   InterPro; IPR026055; FAR.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   NCBIfam; TIGR01488; HAD-SF-IB; 1.
DR   PANTHER; PTHR11011:SF45; FATTY ACYL-COA REDUCTASE; 1.
DR   PANTHER; PTHR11011; MALE STERILITY PROTEIN 2-RELATED; 1.
DR   Pfam; PF12710; HAD; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   SUPFAM; SSF56784; HAD-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:SEF16872.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198812}.
FT   DOMAIN          17..332
FT                   /note="Thioester reductase (TE)"
FT                   /evidence="ECO:0000259|Pfam:PF07993"
SQ   SEQUENCE   771 AA;  85913 MW;  8418844C6737FC62 CRC64;
     MTPHHANTEL GDAHVLLTGA TGFVGQAVLE RLLRDHPATR ISLLVRRKGS QTGQDRLRQL
     LRKPVFRRWR DTVGAEEADR IVRARITVLE GSVTRVPELP ADLDVVIHSA STVSFDPPIH
     EAFDTNVNGA VGLYKALLAS GSDPHVVHVS TCYVGGLRRG VVPEARLEHD VLWHTEWTLA
     TRIHEQAELT SREPAMLERF MSRARGDHGK EGPIAAARAS ENARREWVRS RLVAAGRRRA
     QSLGWTDVYT LTKALAERAA EDLWGEAGHR LSVVRPAIIE SALRHPFPGW IDGFKVADPL
     IFAYGRGQLP DFPGLPDSIL DVIPVDLVVN AILAVAANPA PVDEPRYFHI ASGASNPLPF
     HRMYENVRDY YTQHPLPKDG GFVEVPDWKF SGERRFNRVL RLARTKADLW DAALRLMPNN
     ERKRALATGN AKLRAGIATL GNFVDLYRAY AQTEIVFDDR NARALNNALP AGVREDRGFG
     VERIDWEGYL QKVHLPAITE LTAAHRRRRA ATVRPPGARP RRELPRRTDV LAVFDLERTV
     VDSNIVEQYL WVRTAGFRKA AWPKEVADLL VSLPGYLRAE RRDRGEFIRA FLRRYRGMPV
     ARLEEVVRSG YADTMLRHTS ADALARIREH RAAGHRTVLV TGSAGLLAAP LADLFDEVVG
     SSMHVRDGVL TGYLAKPPLV DEARAAWLLR YAEEGGYDLA ASYGYGDSHS DLPWLSLLGK
     PSAINPDAEL ARASHRRNWD IHRWKSGGAG VRREVIAARA TNPTRTDGKS D
//