ID   A0A1H5PTH7_9ACTN        Unreviewed;       378 AA.
AC   A0A1H5PTH7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Germicidin synthase {ECO:0000313|EMBL:SEF17173.1};
GN   ORFNames=SAMN05216533_8187 {ECO:0000313|EMBL:SEF17173.1};
OS   Streptomyces sp. Ag109_O5-10.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1855349 {ECO:0000313|EMBL:SEF17173.1, ECO:0000313|Proteomes:UP000198812};
RN   [1] {ECO:0000313|EMBL:SEF17173.1, ECO:0000313|Proteomes:UP000198812}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ag109_O5-10 {ECO:0000313|EMBL:SEF17173.1,
RC   ECO:0000313|Proteomes:UP000198812};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNTQ01000001; SEF17173.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5PTH7; -.
DR   STRING; 1855349.SAMN05216533_8187; -.
DR   Proteomes; UP000198812; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198812}.
FT   DOMAIN          89..226
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   ACT_SITE        164
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   378 AA;  40593 MW;  BB7E1C8846225E94 CRC64;
     MKTGEILAEV RSRHPQATWL SRIDGIAAST GIDSRGWMLP LETAAAPGSG SGLRTPRAGQ
     ARTALAGSGF TEREVNRAIA ALEAIPAPQT VQERTAPAWA AVQTYGERAA RDALRAAGLD
     TSDVDCVITS HSTTPALPGL DLSLLNRLEL PADVLLLPAT QWACIAGTRS LALAADLVAA
     DPDRVVLVVI SEALSTTYQP ADDTLESLIV RLLFADTAVA VVVTGRPRPE SVLRLDAAWH
     HTLPGTTDLH RLETREDGTH FVMDRRGPRA VQQTVAAMWE WLRARHQDDG RSWHPDLLLA
     HPGGTRVLEY MEQTMPDSWP EGLLAYSRDS YTSGNRGGAA VLDILRRAHD AGQKPGSRTV
     LYAAAPGLTA TALEGEWL
//