ID   A0A1H5S3N1_9SPHI        Unreviewed;       475 AA.
AC   A0A1H5S3N1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=HDIG domain-containing protein {ECO:0000313|EMBL:SEF45253.1};
GN   ORFNames=SAMN05421877_101158 {ECO:0000313|EMBL:SEF45253.1};
OS   Sphingobacterium lactis.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Sphingobacterium.
OX   NCBI_TaxID=797291 {ECO:0000313|EMBL:SEF45253.1, ECO:0000313|Proteomes:UP000236731};
RN   [1] {ECO:0000313|Proteomes:UP000236731}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22361 {ECO:0000313|Proteomes:UP000236731};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC       polymerase family. {ECO:0000256|RuleBase:RU003953}.
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DR   EMBL; FNUT01000001; SEF45253.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5S3N1; -.
DR   Proteomes; UP000236731; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR   GO; GO:0042245; P:RNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   CDD; cd00077; HDc; 1.
DR   CDD; cd05398; NT_ClassII-CCAase; 1.
DR   Gene3D; 1.10.246.80; -; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR   Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR002646; PolA_pol_head_dom.
DR   InterPro; IPR032828; PolyA_RNA-bd.
DR   NCBIfam; TIGR00277; HDIG; 1.
DR   PANTHER; PTHR47545; MULTIFUNCTIONAL CCA PROTEIN; 1.
DR   PANTHER; PTHR47545:SF1; MULTIFUNCTIONAL CCA PROTEIN; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF01743; PolyA_pol; 1.
DR   Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE   3: Inferred from homology;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   RNA repair {ECO:0000256|ARBA:ARBA00022800};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU003953};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          255..379
FT                   /note="HD/PDEase"
FT                   /evidence="ECO:0000259|SMART:SM00471"
SQ   SEQUENCE   475 AA;  54207 MW;  E850DB1C69AE89CD CRC64;
     MHFVAMSENL SHPIFPIIKD LTKQEGVSCY VIGGFVRDHI MGRPFKNDID IVVLGSGIDF
     ANKLGEILQA KVTVFKSFGT AMLQYDGLQI EFVGARKESY RQDSRKPIVE DGTLEDDQNR
     RDFTINAMAY SLNDADYGAL VDPFHGVEDL ENRVIRTPLE PGITFSDDPL RMMRAIRFAT
     QLNFRIDSLA LDAISSHADR IKIISRERVI DELNKIILAE KPSIGFKYLF DTGLLERIFP
     AMHQLHGVEV IEGKGHKDNL YHTLEVLDNV AEMSDDLWLR WAAIMHDIAK PATKRFDKKV
     GWTFHGHEDR GAKMVPKLFA DLKLPLNEKM KFVQKLVMLH LRPIVLVKDI VTDSAVRRLL
     FEAGDDIDAL MMLCHADVTT KNDYKKKKYR ENFELVKQKL KDVEERDHLR NWQPPIDGED
     IMQAFGIGPS RHVGMIKNAI REAILEGDIP NSREEAMRFM LEKGKNLGLN PVNGN
//