ID   A0A1H5UQK3_9CLOT        Unreviewed;       629 AA.
AC   A0A1H5UQK3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Multicomponent Na+:H+ antiporter subunit D {ECO:0000313|EMBL:SEF77309.1};
GN   ORFNames=SAMN05660865_00976 {ECO:0000313|EMBL:SEF77309.1};
OS   Caloramator fervidus.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Caloramator.
OX   NCBI_TaxID=29344 {ECO:0000313|EMBL:SEF77309.1, ECO:0000313|Proteomes:UP000242850};
RN   [1] {ECO:0000313|Proteomes:UP000242850}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5463 {ECO:0000313|Proteomes:UP000242850};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
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DR   EMBL; FNUK01000010; SEF77309.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H5UQK3; -.
DR   OrthoDB; 9807568at2; -.
DR   Proteomes; UP000242850; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR   InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   PANTHER; PTHR42682; HYDROGENASE-4 COMPONENT F; 1.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   PRINTS; PR01437; NUOXDRDTASE4.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242850};
KW   Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        32..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        167..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        211..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        253..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        278..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        311..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        341..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        378..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        459..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        528..550
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        609..628
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          133..425
FT                   /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT                   subunit"
FT                   /evidence="ECO:0000259|Pfam:PF00361"
SQ   SEQUENCE   629 AA;  68858 MW;  34A5631E9316A30D CRC64;
     MQHYPILSIV TLFLGAFLTV IFGSKNETVR KFIALVASSI SLILVLMLIK PVMIENNVIQ
     YWMGNWRPIH DWAIGIGLEV DSLGLFFGII AVVTIFLSIV FSFRYTEKDS ETDKYYVLFL
     MLSGSVLGLV FTGDLFNMFV MIEIMTFAAV GLTAFRNYQE GALEAALKYL VLGSIGSSLV
     LAGTITIYSQ VHTLNMAQIS ALLFNNLTPS TLFAFALLLA GYSLKAFVVP FHPAAPDAYM
     SAPSSISMAF SGMVNKAGVY AIIRLVYVLY HAMSFKSIQL LLIIIGTITM FVGVTMALAQ
     NDFKRLLAFH SISQIGYVIT AVGVSTALGL TAGLYHALNH TLFKGLLFLT AGAVFYATGT
     TDLNKLGGLA KKMPQTAAVF LIGAFSISGL PPFNGFVSKW LVYQATYQAN LAPVTIVALL
     VSVMTLASFI KVAQSIFFGQ MPKEFENVKE VPLSMRIPMW IMAILCVLTG IFPNFVTKYL
     ISPAVSAALN VGKYIDIMMG NGYAEKILGK PVEIPAVDYV LAGYWNPVAW LVLFALLLLA
     VTIVAVAGGF NTASLPVDGD DSKYEVFFGG EANEYSHVKG NDLFWGLKYD LRHYFGFMHD
     AHSGIINDYA LWAIFTTTIF IVYIFLLVP
//