ID A0A1H5VK65_9FIRM Unreviewed; 286 AA.
AC A0A1H5VK65;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:SEF87600.1};
GN ORFNames=SAMN05216537_11185 {ECO:0000313|EMBL:SEF87600.1};
OS Lachnospira multipara.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnospira.
OX NCBI_TaxID=28051 {ECO:0000313|EMBL:SEF87600.1, ECO:0000313|Proteomes:UP000236726};
RN [1] {ECO:0000313|EMBL:SEF87600.1, ECO:0000313|Proteomes:UP000236726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D15d {ECO:0000313|EMBL:SEF87600.1,
RC ECO:0000313|Proteomes:UP000236726};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNUL01000011; SEF87600.1; -; Genomic_DNA.
DR RefSeq; WP_051195391.1; NZ_FNUL01000011.1.
DR AlphaFoldDB; A0A1H5VK65; -.
DR STRING; 1410661.GCA_000702205_01759; -.
DR Proteomes; UP000236726; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000236726}.
FT DOMAIN 4..286
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 286 AA; 31373 MW; 3083AEA7DAA969C7 CRC64;
MEDVKVGFIG FGLIAGSIAH ALKETKKPYT IIATSRRIDP ILKAKEDGVV DTACECIDDN
FKDCDIIILC TPVVTITSYL CKLKSIIKPG CIITDVGSVK TIIHKEVSKL GLDNCFIGGH
PMAGSEKTGY ENSSSAILNN AKYIITPTPL TTMEQLNFFQ DFVRDTTAKP LIMDYETHDR
TVAGISHLPH LISTALVKVV SENDDPEGHM HCLAAGSFRD MSRVAASSPE MWEQICISNS
DAISGLLGQY IDILNEIKTN LDNKTPGYVA SLFEDSRHYK LDKKVD
//
