ID A0A1H5WLX9_9EURY Unreviewed; 221 AA.
AC A0A1H5WLX9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Translation initiation factor 6 {ECO:0000256|HAMAP-Rule:MF_00032};
DE Short=aIF-6 {ECO:0000256|HAMAP-Rule:MF_00032};
GN Name=eif6 {ECO:0000256|HAMAP-Rule:MF_00032};
GN ORFNames=DV707_01150 {ECO:0000313|EMBL:QCC46394.1}, SAMN04488133_1329
GN {ECO:0000313|EMBL:SEG00649.1};
OS Halobellus limi.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Halobellus.
OX NCBI_TaxID=699433 {ECO:0000313|EMBL:SEG00649.1, ECO:0000313|Proteomes:UP000236740};
RN [1] {ECO:0000313|EMBL:SEG00649.1, ECO:0000313|Proteomes:UP000236740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10331 {ECO:0000313|EMBL:SEG00649.1,
RC ECO:0000313|Proteomes:UP000236740};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QCC46394.1, ECO:0000313|Proteomes:UP000296733}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10331 {ECO:0000313|EMBL:QCC46394.1,
RC ECO:0000313|Proteomes:UP000296733};
RX PubMed=30975999; DOI=.1038/s41467-019-09390-9;
RA Xiong L., Liu S., Chen S., Xiao Y., Zhu B., Gao Y., Zhang Y., Chen B.,
RA Luo J., Deng Z., Chen X., Wang L., Chen S.;
RT "A new type of DNA phosphorothioation-based antiviral system in archaea.";
RL Nat. Commun. 10:1688-1688(2019).
CC -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC association with the 30S ribosomal subunit to form the 70S initiation
CC complex. {ECO:0000256|HAMAP-Rule:MF_00032}.
CC -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000256|HAMAP-
CC Rule:MF_00032}.
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DR EMBL; CP031311; QCC46394.1; -; Genomic_DNA.
DR EMBL; FNVN01000001; SEG00649.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H5WLX9; -.
DR KEGG; hlm:DV707_01150; -.
DR OrthoDB; 33582at2157; -.
DR Proteomes; UP000236740; Unassembled WGS sequence.
DR Proteomes; UP000296733; Chromosome.
DR GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0042256; P:cytosolic ribosome assembly; IEA:InterPro.
DR HAMAP; MF_00032; eIF_6; 1.
DR InterPro; IPR002769; eIF6.
DR NCBIfam; TIGR00323; eIF-6; 1.
DR PANTHER; PTHR10784; EUKARYOTIC TRANSLATION INITIATION FACTOR 6; 1.
DR PANTHER; PTHR10784:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 6; 1.
DR Pfam; PF01912; eIF-6; 1.
DR PIRSF; PIRSF006413; IF-6; 1.
DR SMART; SM00654; eIF6; 1.
DR SUPFAM; SSF55909; Pentein; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540, ECO:0000256|HAMAP-
KW Rule:MF_00032};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917, ECO:0000256|HAMAP-
KW Rule:MF_00032}; Reference proteome {ECO:0000313|Proteomes:UP000236740}.
SQ SEQUENCE 221 AA; 22678 MW; C63BCD6282B30489 CRC64;
MLRASFAGSP YVGVFARATD HVLIVRSDAE SDVVDAMTEE LDVPAVAATV GGSGTVGALA
TGNENGILVT SRATEREKEA IESAAEVPVA ELPGRINAAG NVVLANDYGA YVHPELSDEA
VDVVESTLEV PVEHGSLADV QTVGTAAVAT NEGALCHPKS REPELEALEA HLDVRADIGT
INYGAPLVGS GLVANEAGYV AGEDTTGPEL SRIEDALGYL E
//
