ID A0A1H5X4Q8_9ACTN Unreviewed; 1006 AA.
AC A0A1H5X4Q8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Exonuclease SbcC {ECO:0000313|EMBL:SEG06256.1};
GN ORFNames=SAMN04489712_10371 {ECO:0000313|EMBL:SEG06256.1};
OS Thermomonospora echinospora.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=1992 {ECO:0000313|EMBL:SEG06256.1, ECO:0000313|Proteomes:UP000236723};
RN [1] {ECO:0000313|Proteomes:UP000236723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43163 {ECO:0000313|Proteomes:UP000236723};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNVO01000003; SEG06256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H5X4Q8; -.
DR OrthoDB; 9795626at2; -.
DR Proteomes; UP000236723; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR32114; ABC TRANSPORTER ABCH.3; 1.
DR PANTHER; PTHR32114:SF2; ABC TRANSPORTER ABCH.3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Exonuclease {ECO:0000313|EMBL:SEG06256.1};
KW Hydrolase {ECO:0000313|EMBL:SEG06256.1};
KW Nuclease {ECO:0000313|EMBL:SEG06256.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000236723}.
FT DOMAIN 5..182
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT REGION 220..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 476..503
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 585..699
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 372..390
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1006 AA; 108206 MW; 5506C079225328C2 CRC64;
MRLHRLEITA FGPFSGTETI DFAALSDAGL FLIHGQTGAG KTSVLDAVCF ALYGKVPGVR
GKADGLRSDH AAPGVAPQVV LETTIRGRRF RFTRWPAWER PKLRGSGTVR ENARVLVEEL
ASGRWSGLSS RLDEAGDLVE RLLGMNAVQF CQVVLLPQGE FAAFLRAGAE ERRKVLERLF
AAEVYARVEK WLVDSRVETG RQAARLRAAA ESEADRIAEV AGAQRPGAGP VPSPRRAEPG
EQPPEPVEEL VPWAAELAGQ LAAVRSVARD LSAEYSAALV QAREADEQGR ALADRQRRHA
DAQRRHDALA GRSAERAALA ARLEAAVRAD RVMPLIDAAA DRERRAERAR RRATEARAAV
GALAPGAAPE DVLGKAERDR RDEAAGLEGL REEAARERRL TAEAAGLARD AERLQAGEEE
LRTQLEELPA RVEEHRAALE AVRLRVAGRP AARQAVHDAM ERVDKARRRE TVTAALARAE
EEQRAAVDRA QELRDRLQAI RQTRLDGMAA ELAAELAAGE PCLVCGSREH PAPATAHADA
PTREDEEAAQ RSYDRAQAAR EQGGARVAEL RAERDGLLEI TQEPLDALVA ALEEAQAALK
ALDAEAAEAD GLQQRLVRAE RELSQARQER ETVLQRLAGT RTRYEELTTE AARLRERLDE
ARGDDPTLEA RIDRLSGEAE ALRAAVEAAR DEAGAAEALA DARAAAGRAA EDAGFDGVEQ
ARAAALTEAA RDGLQQRIRA FDTEEAAVRA ALADPELVAA AALPTPDLDA LRAAFEAAQH
EHNEAFNALR KAQDRCDRLA ELGGRLAAAV AAWRPVAERH AVAFRLAGLA SGQHPDNHRR
MRLSAYVLAA RLEQVVAAAN ERLARMSAGR YALEHTTDKA AADGRRGGTG GLGLRVADAW
TGQSRDPVTL SGGESFITSL ALALGLADVV TAESAAGTEI GTLFVDEGFG TLDEETLDEV
MGVLDGLRDG GRAVGIVSHV VELRARIPAQ LRVRKERTGS TATVTV
//
