ID A0A1H6BL68_9GAMM Unreviewed; 345 AA.
AC A0A1H6BL68;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=SAMN05444390_102731 {ECO:0000313|EMBL:SEG61440.1};
OS Marinobacterium lutimaris.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinobacterium.
OX NCBI_TaxID=568106 {ECO:0000313|EMBL:SEG61440.1, ECO:0000313|Proteomes:UP000236745};
RN [1] {ECO:0000313|EMBL:SEG61440.1, ECO:0000313|Proteomes:UP000236745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22012 {ECO:0000313|EMBL:SEG61440.1,
RC ECO:0000313|Proteomes:UP000236745};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC {ECO:0000256|ARBA:ARBA00034754}.
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DR EMBL; FNVQ01000002; SEG61440.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6BL68; -.
DR OrthoDB; 9770982at2; -.
DR Proteomes; UP000236745; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd18138; HLD_clamp_pol_III_delta; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR032780; DNA_pol3_delt_C.
DR InterPro; IPR010372; DNA_pol3_delta_N.
DR InterPro; IPR005790; DNA_polIII_delta.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01128; holA; 1.
DR PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR Pfam; PF14840; DNA_pol3_delt_C; 1.
DR Pfam; PF06144; DNA_pol3_delta; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000236745}.
FT DOMAIN 22..191
FT /note="DNA polymerase III delta N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06144"
FT DOMAIN 217..337
FT /note="DNA polymerase III subunit delta C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14840"
SQ SEQUENCE 345 AA; 38811 MW; DE71506C7051BEE1 CRC64;
MKLKPEQLGS QLKRQQEALP VYLVTGDEPL LCGESIDAIR AHLRHLGFTE REVMHVDAGF
SWDSLLESAN ALSLFAERKI IEIRLGSQKL NKAASDLLQK YLANPAPDNA LLIVCDRMDR
SVKQSAWFKK VEQCGAVVEV WPIEADQLVQ WLGQRAASQG VQLEPEALQL MADRIEGNLL
AARQELDKLA LLYPGQRLNA EQVVQAVSDS SRFDIFALTD AALQADAGRC QHILQVLRQE
GNEAPVVLWA LTRDIRMLHR VIRGVANGQA WDTLCQRERI FGKRKNLVRN ATRRLRPEQL
EQLLDLASDV DMAIKGQRPD DPWLLLNQIT LALGGCQLPW RQALD
//
