ID   A0A1H6CDT0_9ACTN        Unreviewed;       739 AA.
AC   A0A1H6CDT0;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Anaerobic selenocysteine-containing dehydrogenase {ECO:0000313|EMBL:SEG71114.1};
GN   ORFNames=SAMN04489712_109242 {ECO:0000313|EMBL:SEG71114.1};
OS   Thermomonospora echinospora.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Thermomonospora.
OX   NCBI_TaxID=1992 {ECO:0000313|EMBL:SEG71114.1, ECO:0000313|Proteomes:UP000236723};
RN   [1] {ECO:0000313|Proteomes:UP000236723}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43163 {ECO:0000313|Proteomes:UP000236723};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; FNVO01000009; SEG71114.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6CDT0; -.
DR   OrthoDB; 7376058at2; -.
DR   Proteomes; UP000236723; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02782; MopB_CT_1; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 2.20.25.90; ADC-like domains; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   PANTHER; PTHR43105:SF14; POSSIBLE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236723}.
FT   DOMAIN          2..59
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
SQ   SEQUENCE   739 AA;  78649 MW;  EB059AC7F9FEF028 CRC64;
     MSRTAYRTCP LCEALCGLEL ILDGDDRITG VRGDFADPFS KGFVCPKGAT LGRLDGDPDR
     LAVPLLRDGD GHTETGWDEA FAAVRRGLRE VVERHGRDAV AVYVGNPTAH SIAGPLYGGA
     IIKALGTRNV YSASTADQMP KHVSAGYMFG DPVAIPVPDL DRTDHLLMLG ANPLESNGSL
     CSAPDFPGRL KAIRARGGRV TVVDPRRTRT AALADQHVPI RPGTDAHLLL ALVHTLFAED
     LVDLAHLAGR VHGLDELRAL AVDFTPELVT GITGIRPLQI RRMARELAAA ERAAVYGRIG
     TCTQAHGTLG SWLIDVLNIL TGNLDRPGGA MFPRAAHVPV YRRKRPFTTG RWRSRVRDLP
     EVLGEFPVAT LADEILTPGE GQIRALVTIG GNPALSAPNA DRLDAAMAGL EFMVSVDPYL
     NETTRHAHVV LPPPRPAQTP HYDVALLGFT VRNYARYSAP VVPLPEGRPS EAEILARLAL
     LASGADGDPA ALDEMIVGDT LAKAVAMPGS PVHGREPEEL RKSLTGRGAE LRLDMMLRLG
     PYGEGFGADP EGLTLARLRD EHPHGIDLGP LEPRLDEVLC TASGLVELCP PSFAADADRL
     RADLGAPAPQ GLVLIGRRHL RSNNSWLHNV PELVGGSNRC TLQLNPADAA RLGVAAGDLV
     RVTSRAGTLD AVAEPTDTVM TGVVSLPHGW GHDRPGTRTR VAGEHAGVNV NAVTDEQEID
     PLSGNAVFNG VPVTVEHLG
//