ID A0A1H6CL97_9ACTN Unreviewed; 205 AA.
AC A0A1H6CL97;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=DNA-binding transcriptional regulator, AcrR family {ECO:0000313|EMBL:SEG73473.1};
GN ORFNames=SAMN04489712_110114 {ECO:0000313|EMBL:SEG73473.1};
OS Thermomonospora echinospora.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=1992 {ECO:0000313|EMBL:SEG73473.1, ECO:0000313|Proteomes:UP000236723};
RN [1] {ECO:0000313|Proteomes:UP000236723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43163 {ECO:0000313|Proteomes:UP000236723};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNVO01000010; SEG73473.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6CL97; -.
DR OrthoDB; 3426391at2; -.
DR Proteomes; UP000236723; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF223; HTH-TYPE TRANSCRIPTIONAL REGULATOR UIDR; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335,
KW ECO:0000313|EMBL:SEG73473.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000236723};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..70
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 33..52
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 205 AA; 22711 MW; 8B20A5158FB3A319 CRC64;
MRTVDPERHR RRRRQIIEAA TGLFATKGLA KTTTAEICRA AGMSSGNLFH YFPSKQAIFY
GMFELDRDGW DAEFQAAGTD PDPWAALMRV VDRLAAEAAH PLMAGLLVEV LAQAHRDPEV
AALVAETDRR LFRGVAMLVE RLQKEGLADP GLPPDTAARW VVVITEGFHT RGYTEPDRDH
AAEVATAKEL IARALRYTGP ETSDR
//
