ID A0A1H6DRZ0_9ACTN Unreviewed; 890 AA.
AC A0A1H6DRZ0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Acetyl coenzyme A synthetase (ADP forming), alpha domain-containing protein {ECO:0000313|EMBL:SEG88071.1};
GN ORFNames=SAMN04489712_12169 {ECO:0000313|EMBL:SEG88071.1};
OS Thermomonospora echinospora.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=1992 {ECO:0000313|EMBL:SEG88071.1, ECO:0000313|Proteomes:UP000236723};
RN [1] {ECO:0000313|Proteomes:UP000236723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43163 {ECO:0000313|Proteomes:UP000236723};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNVO01000021; SEG88071.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6DRZ0; -.
DR Proteomes; UP000236723; Unassembled WGS sequence.
DR GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:InterPro.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR043938; Ligase_CoA_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF19045; Ligase_CoA_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000236723}.
FT DOMAIN 20..173
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 890 AA; 92115 MW; DAA8B84E10BF16A8 CRC64;
MSAPMTDAGE HALLRDGSMV HIRPLARSDR TALHGLVDRL SDQSAYLRFF TGGLRTPHAY
IDRLTGDGWP GHALVALVGG QMMGLAELIP AGGGTSAEIG VLVDDRMHGR GLGTLLLEQL
AIEASAHGIT EFTATVLAEN TAMTTLLATA GFQVRRSGSR EYDIRFPLAC TGELTAAIEA
REHTAGAASL RRVMRPGSVA VIGAGRDPRN VGHRILRNLL NGGYRGPIYP VNPYADKILG
LPAFPSVSAI PGEVGLAVVA TPAEAVPEVA RQCAEHGVQA LVVVTAGFAE TGGEGARREA
ELLAICRDAG MRLVGPNCLG IVNTAEGLNA SFLPAMPTRG RLAVMSQSGA VGLALLEQAG
ATGLGVSGFV SAGNKADISG NDLLQYWEDD PDTSVIALYL ESFGNPRKFA TLARRVGARK
PVVTLKSGRS DAGGRAVRSH TAAAATSDIA VDALLRRAGV VRAETVRDLL DTARLLAHQP
LPRGRRVAVV GNSGGPGVLA ADACAALGLE VPELAEPIRR ALREALGPSA AVANPVDLTA
DGGAAQLTEA LRVVLDDPGI DAVIAVYTPP FGSGAEASKA AIAAAARGSG KPVLACVVGE
DSLIDDGTVQ VPAYAYPEQA VTALRHAVDQ AEWRSRPTAP AAEPDGVRRR QARSLIEAEL
RFAPAGRWLD PETTHRLLDH YGITMVETIS VDGAECAVEA AALTGCPVAL KATGPALVHK
SDVGGVRLGL QTPEQVRDAY RSMAAALGEA MTGAVVQRMA GEGVEVIVGA LEDPAFGPLI
MVGMGGTAAD LLGDRVFRAA PLHAGEAGEM IRSLRCAPLL SGYRGRPPAA VSALEDQVTR
VAWLVADNPE IAELDLNPVI VTTGGTVTVD ARIRLAPPPP APSPIDRALG
//
