ID A0A1H6E604_9ACTN Unreviewed; 431 AA.
AC A0A1H6E604;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SEG92315.1};
GN ORFNames=SAMN05216223_125125 {ECO:0000313|EMBL:SEG92315.1};
OS Actinacidiphila yanglinensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=310779 {ECO:0000313|EMBL:SEG92315.1, ECO:0000313|Proteomes:UP000236754};
RN [1] {ECO:0000313|EMBL:SEG92315.1, ECO:0000313|Proteomes:UP000236754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.2023 {ECO:0000313|EMBL:SEG92315.1,
RC ECO:0000313|Proteomes:UP000236754};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNVU01000025; SEG92315.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6E604; -.
DR OrthoDB; 144293at2; -.
DR Proteomes; UP000236754; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SEG92315.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000236754};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 186..253
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 290..381
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
FT REGION 329..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 43600 MW; B407F8300C915EC6 CRC64;
MTNTWSATGQ DRFRFTRRDL TGAFAMVLCM AVSVVAAPGT VLKVVVAVLG VFAELGMLLG
RRILAPDRAV FGVGLTIATG FAIILLAPQG LGEIPVLAGA AVLPLCVPDG PVRGAAVAVV
AVGFGVAIMV ISGSVVGLLA GVGAWFIADR TVEHAALQAE RDRAVALLAE LEANRLARLE
AAAVEERGRI AREMHDVLAH SLAGLSVQLQ AVRAVAAREG ASPVLTEPLD RAAELARDGV
QEARAAVGAL RAGPLRSIDD LAALVSGFPG NAQLRVTGRP GRLAPEAGHA VYRAVQEALT
NSARYATGSA VEVNVAWDAG EVRVAVRDHG LPAGRSPSGV QGSGSGLHGM TERIEQAGGS
VSAGPASDAP GWRVTLRVPV AASGAPLAPA RPESRTPAPD AEGGTEGDTS SDAANGRDDG
GAGGADGKMG E
//
