ID   A0A1H6E9F7_9ACTN        Unreviewed;       347 AA.
AC   A0A1H6E9F7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=C-methyltransferase {ECO:0000313|EMBL:SEG93576.1};
GN   ORFNames=SAMN05216223_12819 {ECO:0000313|EMBL:SEG93576.1};
OS   Actinacidiphila yanglinensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=310779 {ECO:0000313|EMBL:SEG93576.1, ECO:0000313|Proteomes:UP000236754};
RN   [1] {ECO:0000313|EMBL:SEG93576.1, ECO:0000313|Proteomes:UP000236754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2023 {ECO:0000313|EMBL:SEG93576.1,
RC   ECO:0000313|Proteomes:UP000236754};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNVU01000028; SEG93576.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6E9F7; -.
DR   OrthoDB; 3862772at2; -.
DR   Proteomes; UP000236754; Unassembled WGS sequence.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.1350; -; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR016461; COMT-like.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR   PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   PIRSF; PIRSF005739; O-mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51683; SAM_OMT_II; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SEG93576.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236754};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000313|EMBL:SEG93576.1}.
FT   DOMAIN          119..326
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
SQ   SEQUENCE   347 AA;  36820 MW;  C2DB7AD6EDF7B024 CRC64;
     MTEAQQATTT VPGPVLRLRE FAHSAACAAS VRAAALLGLP EALGDEPASP ADLAAAVGAD
     PDATARLLRS LAVHGVFTED ADGNYAHTPE SRLLREDAPH SIKYNVLWAT EPWTWELLQH
     LDEGVRTGKA VFPSLHGGEE FFSHLHSHTP RSAEVFDKAM TQSSHLSARA IAERLDLSGA
     GTVADIAGGQ GLVLATLLEK HAGLHGTLLD LPNVVANPDP RLAAGGAFAS RTRLLPGDCL
     QGIPVEADVY IFKNILEWDD ESTVTALRNA VAAGRPGARV IVIENLVDGS PEMKFTTAMD
     LLLLLNVGGK KHTRKGLAAL MEKAGLRVDR ISAVNSYLHM FEAVIPG
//