ID   A0A1H6EE43_9ACTN        Unreviewed;       352 AA.
AC   A0A1H6EE43;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:SEG95259.1};
GN   ORFNames=SAMN05444920_10917 {ECO:0000313|EMBL:SEG95259.1};
OS   Nonomuraea solani.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=1144553 {ECO:0000313|EMBL:SEG95259.1, ECO:0000313|Proteomes:UP000236732};
RN   [1] {ECO:0000313|EMBL:SEG95259.1, ECO:0000313|Proteomes:UP000236732}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.7037 {ECO:0000313|EMBL:SEG95259.1,
RC   ECO:0000313|Proteomes:UP000236732};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNVT01000009; SEG95259.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6EE43; -.
DR   OrthoDB; 9798934at2; -.
DR   Proteomes; UP000236732; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   CDD; cd06288; PBP1_sucrose_transcription_regulator; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR   PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236732};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          6..63
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50932"
SQ   SEQUENCE   352 AA;  37819 MW;  8BA327D02D7AA395 CRC64;
     MSPRRVTLAD VAKAAGVSRP TASLVLSGRG RELRISQDVE QRVVRAADEL QYRPNIVSVG
     LRKGTSQTIG FVSDTVATSR LAGDMIKGAL EAARERGFML FIGETEGDAE LERLLLQAMH
     DRQVDGLILA SMFTRTIKVP KSITAASAVL LNALPEQPTP LPSVLPDEVE AGRRAARVLL
     DAGHREGIYL IGEGPRVRDV TRESVAAVER LVGIREALGE AGVKVAGGRT CPDWQPEHGL
     AATRDLLRTA RPRALICFND RIAMGAYQAL DDAGLGVPGD VSVVSFDDHP IASWIRPGLT
     TVALPHYELG RKAVDVLFAQ MNGDHPDPDR LGEVHRVPMP LRTRGSIAPP AG
//