ID A0A1H6EEG3_9ACTN Unreviewed; 900 AA.
AC A0A1H6EEG3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=DNA-binding transcriptional activator of the SARP family {ECO:0000313|EMBL:SEG95346.1};
GN ORFNames=SAMN05444920_10944 {ECO:0000313|EMBL:SEG95346.1};
OS Nonomuraea solani.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=1144553 {ECO:0000313|EMBL:SEG95346.1, ECO:0000313|Proteomes:UP000236732};
RN [1] {ECO:0000313|EMBL:SEG95346.1, ECO:0000313|Proteomes:UP000236732}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7037 {ECO:0000313|EMBL:SEG95346.1,
RC ECO:0000313|Proteomes:UP000236732};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; FNVT01000009; SEG95346.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6EEG3; -.
DR OrthoDB; 5521887at2; -.
DR Proteomes; UP000236732; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000313|EMBL:SEG95346.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000236732};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 17..89
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|SMART:SM00862"
FT DOMAIN 96..233
FT /note="Bacterial transcriptional activator"
FT /evidence="ECO:0000259|SMART:SM01043"
FT REPEAT 692..725
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 900 AA; 97370 MW; 8F63662E05812124 CRC64;
MLIRLLGPVE VEHSGQTRPV RPPQVALALA ALAWEAGRVV PVESLLARVW GEAVPAGARR
TLYTIITRIR RDVLADEGAV VRRLGGYLLD VDESAVDVAR FRGLAGRAAA APDPVPLLGE
ALALWRGDPL TGLPGAWVER AGHRLRDERK EILLRWARAM TGRDAAAAVT ALSPLAEEYP
LDELVAAALI EALHACGRTA EALARFARVR HTLAEELGVE PGASLRRVHQ TLLRSGDVTE
TARPVPAQLP MPLRCFVGRE AELERLEAMI GRRQAVACAI SGPPGVGKSS LALRWAHLYR
DRFPDGQLYA DLGTADAATI LPGFLSALGV PEARMPSGQA AQIGLYRSLL ACRRVLVVLD
DARDAEQVRP LLATAPGSLT LVTSRAELSG LAVTEGAHLL RLDVLPGADA YRLLAAWLGE
QRPAVEPEAA ALIVRRCGRL PLALAIVAAR LAQRTDLPLA EVAADLERAG ADLEPFAHSD
PAIDLRRVFG RSYESLPAPV ARLFRRLGRH PGPHLPLLAA ASLAALPADR TRELATRLEH
ANLAELRGPG DLRIHDLLRV YAAEQARATD SRSVRRTATR RLLDYYVHTA CAANDLCYPH
RDSLTLDPPA RGTSVERFAG QAEALRWYAD EAAVLPTLLA EAVEAGLDGH VWRLTWAFAE
FMQRRGLWEE TLRGNEVALE AARRLGDRLA RARCHNSIAR AQLRLGRHRE AVEHFERAAE
LHRELGEPGL EAHVHLGLSI VPSENGPAVP LGHTLRALEL FRQAGDIVGE ARALNNAGWL
RAESGAYDEA LADCRRAQRI LADAGYAQGE GLTWDSIAHV LNLKGDLPGA VAGFERAAEL
LRADDDLHAA ADTLVRLGET HLRADDVAAA VTVWKQAAEL YGAVGDPRAD KVRARVSAHL
//
