ID   A0A1H6EX71_9ACTN        Unreviewed;       396 AA.
AC   A0A1H6EX71;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=L-2-hydroxyglutarate oxidase LhgO {ECO:0000313|EMBL:SEH01691.1};
GN   ORFNames=SAMN05444920_121139 {ECO:0000313|EMBL:SEH01691.1};
OS   Nonomuraea solani.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=1144553 {ECO:0000313|EMBL:SEH01691.1, ECO:0000313|Proteomes:UP000236732};
RN   [1] {ECO:0000313|EMBL:SEH01691.1, ECO:0000313|Proteomes:UP000236732}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.7037 {ECO:0000313|EMBL:SEH01691.1,
RC   ECO:0000313|Proteomes:UP000236732};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the L2HGDH family.
CC       {ECO:0000256|ARBA:ARBA00037941}.
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DR   EMBL; FNVT01000021; SEH01691.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6EX71; -.
DR   OrthoDB; 9801699at2; -.
DR   Proteomes; UP000236732; Unassembled WGS sequence.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236732}.
FT   DOMAIN          5..388
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
SQ   SEQUENCE   396 AA;  42136 MW;  F1AA22CA49EB9553 CRC64;
     MTEKIGVVGA GIVGLAVARE LAAVRGAEVT VLEKEGRVGA HQTGHNSGVV HAGIYYPPGS
     LKARLCREGV ALLKEYCAAH GLPYQEAGKL VVASTRAERA PLRALAERAR ANGVPGIAEL
     DGLALREIEP HAIGVGAIHS PHTAICDFPA VAGRLALDVA EMGGSVRLSH PVRAIRERPG
     RVEVLAGRRK FAFDRLVVCG GLGTDAVSRM VGAPGDVRIV PFRGEFYALK GAARDLVRGL
     IYPVPDPRYP FLGVHLTRQI GGGVLVGPNA VLALAYEGYK RRNFRNVGQI LGWPGTLRLA
     RTHWRTGFKE IYGSLVKSVF VREARRYVPE LTAADLERAP GGVRAQAVAR DGRMVDDFVV
     DVHGKVVLVR NAPSPAATSS LAIARHIAGI VPALVR
//