ID   A0A1H6HVG5_9EURY        Unreviewed;       344 AA.
AC   A0A1H6HVG5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=L-threonine aldolase {ECO:0000313|EMBL:SEH38120.1};
GN   ORFNames=SAMN05192561_101320 {ECO:0000313|EMBL:SEH38120.1};
OS   Halopenitus malekzadehii.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halopenitus.
OX   NCBI_TaxID=1267564 {ECO:0000313|EMBL:SEH38120.1, ECO:0000313|Proteomes:UP000199215};
RN   [1] {ECO:0000313|EMBL:SEH38120.1, ECO:0000313|Proteomes:UP000199215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBRC-M10418 {ECO:0000313|EMBL:SEH38120.1,
RC   ECO:0000313|Proteomes:UP000199215};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the threonine aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006966}.
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DR   EMBL; FNWU01000001; SEH38120.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6HVG5; -.
DR   STRING; 1267564.SAMN05192561_101320; -.
DR   OrthoDB; 198122at2157; -.
DR   Proteomes; UP000199215; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   CDD; cd06502; TA_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR023603; Low_specificity_L-TA-like.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; NF041359; GntG_guanitoxin; 1.
DR   PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR   PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   PIRSF; PIRSF017617; Thr_aldolase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199215}.
FT   DOMAIN          8..292
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
FT   MOD_RES         205
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ   SEQUENCE   344 AA;  36479 MW;  F0BFA363704BE6A5 CRC64;
     MKSELDVDLR SDTVTRPSAE MREAAATAEV GDDVYRGDPT VLELERRVAE TLEMEAALYV
     PSGTMGNQIA VQVHTDPGDE VLLEGESHIY RWELGGAAAL SGAQTRPIDA GERGVPTPEQ
     VEAGLVDRDL HRAGTGLFAL ENTHNYRGGK AIPKTRIDDA AAVAHDHEVP VHVDGARLFN
     AAVALDTLAA ELVESVDSVM VCLSKGLGAP VGSMLVGPET FIEEARRVRK LFGGGMRQAG
     LIAAPGLCAL ENVDRLADDH ANAARLARGL DDLDGIEAAD PETNIVVVDV SETGYTAAGF
     LEACTEAGVG GVEFDDYTVR FTTHLDVDRE DIETAIDRIA TIVG
//