ID   A0A1H6IA19_9EURY        Unreviewed;       778 AA.
AC   A0A1H6IA19;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=4-aminobutyrate aminotransferase {ECO:0000313|EMBL:SEH43035.1};
GN   ORFNames=SAMN05192561_101978 {ECO:0000313|EMBL:SEH43035.1};
OS   Halopenitus malekzadehii.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halopenitus.
OX   NCBI_TaxID=1267564 {ECO:0000313|EMBL:SEH43035.1, ECO:0000313|Proteomes:UP000199215};
RN   [1] {ECO:0000313|EMBL:SEH43035.1, ECO:0000313|Proteomes:UP000199215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBRC-M10418 {ECO:0000313|EMBL:SEH43035.1,
RC   ECO:0000313|Proteomes:UP000199215};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00008954}.
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DR   EMBL; FNWU01000001; SEH43035.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6IA19; -.
DR   STRING; 1267564.SAMN05192561_101978; -.
DR   OrthoDB; 6534at2157; -.
DR   Proteomes; UP000199215; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR002575; Aminoglycoside_PTrfase.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR049704; Aminotrans_3_PPA_site.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR45688; ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR45688:SF3; ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL; 1.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   Pfam; PF01636; APH; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:SEH43035.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199215};
KW   Transferase {ECO:0000313|EMBL:SEH43035.1}.
FT   DOMAIN          41..275
FT                   /note="Aminoglycoside phosphotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF01636"
SQ   SEQUENCE   778 AA;  84978 MW;  5B01CDF66F84B71F CRC64;
     MTDAATLIEP FVVQPPTIDE RRAARIAERE FGTQGTATEL GGERDQNFRI DVDDGEAYVL
     KVSSPADDEA SLDLQTEALR HIQRTDPDLP VMEPVPTTDG SLWTTIEDDE TYHVRLFTHV
     PGRPVPGQDL DAEALFKYGA VVARLGKALR GFFHPDADYD ILWDLRHVPE LRSLLDSVTN
     AERRELAERI LDRYEDRVEP EFDSFRAQVI HNDLTLDNVL LNGADRVGGI VDFGDLTHTA
     LVSDLVMAVA SVMYRREDPI EAAQDVIRGY VSVTPLEDEE AELLADLVAA RHLTWGVTVA
     WRLAEHPEKT DAHSVDGVDD GWDLLRSLDE RGLDAVGRRL QAAAKSGAVP YSRTDTSELL
     SRRRDVLGSS PLSYDDPVHF VDGDGVWLFD PDGRQYLDAY NNVPVVGHAN PAVADAIAGQ
     ARTLATNTRY LHEAPVELAD RILATMPEEL DRVLFVNSGS EATDTAWRLA RAATGNGGAI
     VSRNAYHGIT EATTAQSPTI WPEGMDPDHV ETVAPPIDDA HHGDRAGTDP VQKMTESLAT
     LEKRGTETAA WMFDPLFTSD GIHPPDEKRL TSMADRVREA GGLVIADEVQ SGFGRPGEAL
     WGFRNADVVP DVVTLGKPMG NGHPVAAVVT RSDVASALYD RTGFFSTFGG NPVSCVAALA
     VFDEIDDRDL LDHVVDVGAC LGDGLRELGA DHELVGEVRQ SGLMIGVELV RDRETWEPAP
     DETTAVVNGL RERRVLIGST GADGNVLKIR PPLVFERKHA DRLLAALDDV LSELPRHG
//