ID   A0A1H6IQS0_9FLAO        Unreviewed;       274 AA.
AC   A0A1H6IQS0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=UDP-2,3-diacylglucosamine pyrophosphatase LpxH {ECO:0000313|EMBL:SEH51138.1};
GN   ORFNames=SAMN05421793_10879 {ECO:0000313|EMBL:SEH51138.1};
OS   Epilithonimonas hominis.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC   Chryseobacterium group; Epilithonimonas.
OX   NCBI_TaxID=420404 {ECO:0000313|EMBL:SEH51138.1, ECO:0000313|Proteomes:UP000198555};
RN   [1] {ECO:0000313|Proteomes:UP000198555}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19326 {ECO:0000313|Proteomes:UP000198555};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNWX01000008; SEH51138.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6IQS0; -.
DR   Proteomes; UP000198555; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd07398; MPP_YbbF-LpxH; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR043461; LpxH-like.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR34990:SF2; BLL8164 PROTEIN; 1.
DR   PANTHER; PTHR34990; UDP-2,3-DIACYLGLUCOSAMINE HYDROLASE-RELATED; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   4: Predicted;
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          7..204
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
SQ   SEQUENCE   274 AA;  31747 MW;  AEEB519E98D64992 CRC64;
     MKREVEIVII SDLHLGTYGC KAKELLHYLN SIQPKTLILN GDIIDIWQFK KSYFPKSHLK
     VVKKLISFAT KESEVFYITG NHDEAFRNFT DFELGKLKLC NKHVLKLGHK KAWIFHGDAF
     DASVQHSKWI AKLGGKGYDL LIAINNLVNW FLEKIGKEKY SFSKKIKNNV KKAVKYIGDF
     ELTASGLAIE NHFDYVICGH IHQPQIREVT NKKGRCMYMN SGDWVENLTA LEYNGGEWKL
     FVYEDEKHTL KNEEPDEFKK IDSKDLMKIV TQLA
//