ID   A0A1H6IZY3_9FLAO        Unreviewed;       543 AA.
AC   A0A1H6IZY3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Peptidase family M1 {ECO:0000313|EMBL:SEH55101.1};
GN   ORFNames=SAMN05421793_11123 {ECO:0000313|EMBL:SEH55101.1};
OS   Epilithonimonas hominis.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC   Chryseobacterium group; Epilithonimonas.
OX   NCBI_TaxID=420404 {ECO:0000313|EMBL:SEH55101.1, ECO:0000313|Proteomes:UP000198555};
RN   [1] {ECO:0000313|Proteomes:UP000198555}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19326 {ECO:0000313|Proteomes:UP000198555};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNWX01000011; SEH55101.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6IZY3; -.
DR   STRING; 420404.SAMN05421793_11123; -.
DR   Proteomes; UP000198555; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09603; M1_APN_like; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   Gene3D; 2.60.40.1730; tricorn interacting facor f3 domain; 1.
DR   InterPro; IPR045357; Aminopeptidase_N-like_N.
DR   InterPro; IPR042097; Aminopeptidase_N-like_N_sf.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   PANTHER; PTHR11533:SF303; AMINOPEPTIDASE N; 1.
DR   PANTHER; PTHR11533; PROTEASE M1 ZINC METALLOPROTEASE; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   Pfam; PF17900; Peptidase_M1_N; 1.
DR   SUPFAM; SSF63737; Leukotriene A4 hydrolase N-terminal domain; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..543
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011771511"
FT   DOMAIN          46..218
FT                   /note="Aminopeptidase N-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17900"
FT   DOMAIN          265..470
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
SQ   SEQUENCE   543 AA;  62288 MW;  EE4178A0DD00EA51 CRC64;
     MNKLLLLAIL ISGVSQAQFF EEAKPTKIDT LKGSNTEFRN FWDVKKYDIV LEPNFEAKSI
     KGSNKISLTI EKDVVNPVFQ IDLQSPMKAD KITASFPIAE KKIDGDFIFL TTKKKFKKGE
     KYTIAIDYSG NPLIAKHAPW DGGWIFTKDK NGNPWMTAAD EGIGASIWLP VKDIWSDEPD
     NGITFKIITP KDLVGVGNGK LIKEENLGDK KSWLWEVKSP INDYSIIPSI GKYVNFKDTF
     DGEKGKLELD YWVLDYNLDK AKKQFEQVKP MMKAFEHWFG PYPFYEDFYK LVESPHLGME
     HQSNVAYGNK YQNGYLGRDL SGTGIGLKWD YIIIHETGHE WFANNITAKD QADMWIHESF
     TTYSETLFVD YVFGKADGNK YLQGLRGNIQ NDKPIIGTYG IRNEGSSDMY PKGANMIHTI
     RQVINNDEKF RQILRGLNKD FYHQTVTAAQ IQNYFSEKSG IDLKSIFDQY LTTIKIPTLE
     YKQNGNQLTY KWTNVVPNLK LPIRLADGQE LKPTEEWQTA TLKSSDELKV DPNYYIFTKK
     INP
//