ID A0A1H6R7M4_9LACT Unreviewed; 448 AA.
AC A0A1H6R7M4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Basic amino acid/polyamine antiporter, APA family {ECO:0000313|EMBL:SEI51723.1};
GN ORFNames=SAMN04488113_1026 {ECO:0000313|EMBL:SEI51723.1};
OS Alkalibacterium gilvum.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Alkalibacterium.
OX NCBI_TaxID=1130080 {ECO:0000313|EMBL:SEI51723.1, ECO:0000313|Proteomes:UP000198564};
RN [1] {ECO:0000313|Proteomes:UP000198564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25751 {ECO:0000313|Proteomes:UP000198564};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FNYW01000002; SEI51723.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6R7M4; -.
DR STRING; 1130080.SAMN04488113_1026; -.
DR Proteomes; UP000198564; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR PANTHER; PTHR11785; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11785:SF512; SOBREMESA, ISOFORM B; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 448 AA; 48483 MW; 5C82B3AE8CC48DA6 CRC64;
MEKKEHYGLS TAVSMIVGIS IGSGIFFKSD DILKATGGSV WLGVLVFIIG AFCVIFGSIT
LSQLASRSTK EGGIISYYEE FVSSRLASAF GWFQMLVYFP TITAVVSWVS GIYTISLLNF
PSTLELQTLL GFLYLSFFFL MNYLSYKLGG AFQNLTTIVK MIPLIGVALI GLFWTQGAPM
LPKDVVAVES SIVGWGFLAA LAPIAFSFDG WIVSTSITQE VKNHRKTMPL ALTIGPLIVL
SVYLAFFLGM IAIVGTEYIL SAGDQAISQV GYSIFGASGE KILLIFVLIA ILGVVNGISL
GYIRLPQTLA SKHMLPFSGK IAQMNDKKGL SPYSALLAYL ITVFWLVIHF LTQKYNILAG
GDISEIAIVF SYVAYVILYL KVIGLKKTGH IKSAFLGTTA PILGIFGSII ILLGGLTANP
VYSPLFLLFS GTICLLGYFY GVRTNVGR
//
