ID   A0A1H6SSY3_9LACT        Unreviewed;       487 AA.
AC   A0A1H6SSY3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Putative MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:SEI67035.1};
GN   ORFNames=SAMN04488113_10943 {ECO:0000313|EMBL:SEI67035.1};
OS   Alkalibacterium gilvum.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC   Alkalibacterium.
OX   NCBI_TaxID=1130080 {ECO:0000313|EMBL:SEI67035.1, ECO:0000313|Proteomes:UP000198564};
RN   [1] {ECO:0000313|Proteomes:UP000198564}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 25751 {ECO:0000313|Proteomes:UP000198564};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
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DR   EMBL; FNYW01000009; SEI67035.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6SSY3; -.
DR   STRING; 1130080.SAMN04488113_10943; -.
DR   OrthoDB; 9808458at2; -.
DR   Proteomes; UP000198564; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 2.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        101..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        131..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        223..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        391..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        427..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        465..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   487 AA;  51013 MW;  034EDA5CA6496FA1 CRC64;
     MLEKFFHLKE NNTTVGTEIA AGLTTFFAMS YIIFVNPQIL ALTGMPTQAV FLATVISAAV
     GTLILALYAN VPYAQAPGMG LNAFFTYTVV FALGFTWQEA LFMVFLTGVV GILITVTSIR
     KKIIHAIPET LQHAIGGGIG VFIAYIGLKN AELLSFTSEG QSILSVNNEP YTAGKEISGA
     VNTVVTGGGI IPDMGSFTNP YALLALIGLV VTIIMMVAKV KGAILIGIIL TTVIGIPMGV
     TDLSGLSNPS NSILSAFGEL GTTFGAAFGS QGLGSLLADP SRYALILITI FAFTLTDIFD
     TIGTFIGTGR KAGIFTLEDE KAMGKGNGLN TKMEKALLAD TVATSIGAVF GTSPVTTFVE
     STAGIGAGGR TGLTSLTTGT LFMLTAFFSP VMSIVPGAAT APALIVVGIL MMSAFSEIDW
     NNLEEAIPAF FASIFMGFTY SISYGIAAGF LFYIITKVVK GKIRVVHPVL WATTALFIFN
     FVILGLI
//