ID A0A1H6SW48_9PSED Unreviewed; 885 AA.
AC A0A1H6SW48;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN03159495_1450 {ECO:0000313|EMBL:SEI72178.1};
OS Pseudomonas sp. NFR16.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1566248 {ECO:0000313|EMBL:SEI72178.1, ECO:0000313|Proteomes:UP000199219};
RN [1] {ECO:0000313|EMBL:SEI72178.1, ECO:0000313|Proteomes:UP000199219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NFR16 {ECO:0000313|EMBL:SEI72178.1,
RC ECO:0000313|Proteomes:UP000199219};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FNYJ01000001; SEI72178.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6SW48; -.
DR STRING; 1566248.SAMN03159495_1450; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000199219; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SEI72178.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 418..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 658..875
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 885 AA; 96859 MW; 3D336707B9785CE1 CRC64;
MNSNSRADAL LADLPRDDRG RLKVFLGAAP GVGKTYAMLQ AAHTQLRQGV VLRVGVVETH
GRAETESLLV GLPQQPMLRS EYRGVMLEEM DLDGLLLARP KLVLVDELAH TNAPGSRHAK
RWQDIQELLS AGIDVYTTVN VQHLESLNDQ VRGITGVQVR ETLPDWVLQE AYELVLIDLP
PRELLERLRD GKVYVPEQAR AAIDAFFTQT NLTALRELAM QTAAAQVDND LALGYRQMGQ
AAPAVRGRLL VGIDGDDQAD RLVRHASRVA QRRHLPWSLV HVDNGRFFDE LARARLQSAQ
QLAERLGGEV VVLRAPEVAK ALIQHAAERR ASLVLVGQSR PLLRRRLFGG GLASRLLRNA
HGLEINVLDS EARPDQARSA SPHPLVWFDY LLAVLATVGA SALAWAVSSV LALPNISLVF
LAAVLLVAVR SSVGPAMVCS VLSFLAYDFL FIPPNFSLSI QREEDVLTLL FFLLMAALTG
NLAARQRRQL QALRDTQEET SELLDLSKRL TAATDRQAVL SAAEHHLADW RELQICVLDR
DGQQGWKIEV GGSLEFSGSE RAAADWAWQH GQPAGRGTGT LPSGNWWWLP LWVDDAPLAL
LGVRPRDGQS FSPQRRRLLG ALSQPLGQAL ARARLAQDLE AARLHGETEQ LRSALLASVS
HDLRTPLTAM RGSIDSLLAL GEAIPLEDRR ELLEGTRDEA ERLDRYIQNL LDMTRLGHGA
LKLARDWVSP GDIVGSALNR LRAVLAPLHI ETDVPLELPL LYVHAALIEQ ALINVLENAA
RFSPVHGRLQ MAVRVEADEL VFAVSDEGPG IPEDERAKIF DMFYTAARGD RGGQGTGLGL
AICQGMVGAH GGRISVADGI EGRGTCISLH LPLQAQPQAE IEQAV
//
