ID A0A1H6T2E1_9FIRM Unreviewed; 223 AA.
AC A0A1H6T2E1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Hydrogenase nickel incorporation protein HypB {ECO:0000313|EMBL:SEI73396.1};
GN ORFNames=SAMN02910453_1269 {ECO:0000313|EMBL:SEI73396.1};
OS Lachnospiraceae bacterium A10.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1520821 {ECO:0000313|EMBL:SEI73396.1, ECO:0000313|Proteomes:UP000198998};
RN [1] {ECO:0000313|EMBL:SEI73396.1, ECO:0000313|Proteomes:UP000198998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A10 {ECO:0000313|EMBL:SEI73396.1,
RC ECO:0000313|Proteomes:UP000198998};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM
CC subfamily. {ECO:0000256|ARBA:ARBA00006211}.
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DR EMBL; FNYN01000003; SEI73396.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6T2E1; -.
DR OrthoDB; 9802035at2; -.
DR Proteomes; UP000198998; Unassembled WGS sequence.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR GO; GO:0051604; P:protein maturation; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR004392; Hyd_mat_HypB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00073; hypB; 1.
DR PANTHER; PTHR30134:SF2; HYDROGENASE MATURATION FACTOR HYPB; 1.
DR PANTHER; PTHR30134; HYDROGENASE PROTEIN ASSEMBLY PROTEIN, NICKEL CHAPERONE; 1.
DR Pfam; PF02492; cobW; 1.
DR PIRSF; PIRSF005624; Ni-bind_GTPase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Reference proteome {ECO:0000313|Proteomes:UP000198998};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 38..195
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
SQ SEQUENCE 223 AA; 24450 MW; E7EFD404044CCF14 CRC64;
MSKVDILEVK KTILEDNDAD AEVLRGELKE QKLCYLNLMS SPGSGKTTTL LSLLKAIDHR
IEVGVMEADI DSDVDAKTIA DAGYKSIQLH TGGMCHLDAE MSRQGMRGLG CDDLDLVILE
NVGNLVCPAE FDTGAVLNVV ILSITEGDDK PLKYPLVFEQ CDAVIINKID ALPVFDFDFD
KARANIALRN DHATVFPISA KTTEGVDKLA DWIVEKVQEW QGK
//
