ID A0A1H6TFX0_9LACT Unreviewed; 393 AA.
AC A0A1H6TFX0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=23S rRNA (Cytosine1962-C5)-methyltransferase {ECO:0000313|EMBL:SEI76007.1};
GN ORFNames=SAMN04488113_11718 {ECO:0000313|EMBL:SEI76007.1};
OS Alkalibacterium gilvum.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Alkalibacterium.
OX NCBI_TaxID=1130080 {ECO:0000313|EMBL:SEI76007.1, ECO:0000313|Proteomes:UP000198564};
RN [1] {ECO:0000313|Proteomes:UP000198564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25751 {ECO:0000313|Proteomes:UP000198564};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNYW01000017; SEI76007.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6TFX0; -.
DR STRING; 1130080.SAMN04488113_11718; -.
DR OrthoDB; 9805492at2; -.
DR Proteomes; UP000198564; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43042:SF3; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K; 1.
DR PANTHER; PTHR43042; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SEI76007.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SEI76007.1}.
FT DOMAIN 4..65
FT /note="RlmI-like PUA"
FT /evidence="ECO:0000259|Pfam:PF17785"
FT DOMAIN 164..352
FT /note="S-adenosylmethionine-dependent methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF10672"
SQ SEQUENCE 393 AA; 45208 MW; 1B6CE96E57C805F1 CRC64;
MNVLKIKELA TNRIKKGFPL LLELDFVNKD YLVEGEFVKL VDRHNRFVAY GYIGRERKTI
GYVLSLNESI QIDESFFTQL FKAAYDRRTA FYADDQTTAF RFFNGEGDGA GGLTIDYYEG
YYVFSWYSDG IYQQKDMLVE AFKKAVPEFK GIYEKCRYPK APHKSRFIGG DKASEPLVVK
ENGIHYNIYL DEGWMTGLFL DQRNVRRKIM EKWGLGKTVL NAFSYTGAFS VAAAMGGAIK
TVNVDVANRS KERTKEQFDV NGLDSNQHEI RVMDVFSYLD YAKKHRLTFD LIVLDPPTFA
RTKKRTFSVD KDYTELVKEA IHILAPGGLI ITSTNAWNVT RDDFFDSVNQ AFSGLNVDAY
LLEEFHLPED FPVDKQHPES DYLKVFALEK AKK
//
