ID A0A1H6TZH8_9BACT Unreviewed; 549 AA.
AC A0A1H6TZH8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=SAMN05192553_101477 {ECO:0000313|EMBL:SEI83614.1};
OS Cyclobacterium xiamenense.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Cyclobacterium.
OX NCBI_TaxID=1297121 {ECO:0000313|EMBL:SEI83614.1, ECO:0000313|Proteomes:UP000199403};
RN [1] {ECO:0000313|Proteomes:UP000199403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBRC-M 10761 {ECO:0000313|Proteomes:UP000199403};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR EMBL; FNZH01000001; SEI83614.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6TZH8; -.
DR STRING; 1416801.SAMN05192553_101477; -.
DR Proteomes; UP000199403; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:SEI83614.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 322..452
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 549 AA; 63508 MW; 3D23E67AE3B73C3F CRC64;
MVYETPEFVK ISEENHKNHM KRFSNLIAQL DQTNKTGDKL GLLQAYFAQA PDQDRLWTLA
LFTHKRPKRT VTTRQLRDWC CDRAGIPDWL FEESYQTVGD LAETIALVLP DNTERSERSL
HEWIQFLEKL KSQDEDSKKR EIASAWNKLN REERLVFNKL ITGGFRIGVS QQLITRALAS
TFDMEKSALA HRIMGNWSPL ETTFTDLLFE ADLSSDRSRP YPFYLAHPLE GTEALPGSRS
DWLAEWKWDG IRGQLIQRKG EVFIWSRGEE LITDKFPELE QMGKNLPEGT VLDGEIMPFE
NGNPLPFGLL QTRLGRKNVS ARLLREAPVS FMAYDLLEWK GQDVRHWELW KRRETLAALI
HSMPKENLEL SQVLTDSNWA ELAALREQSR SVKAEGLMLK RKDGSYETGR KRGGWWKWKI
DPLTVDGVMI YAQKGHGRRA NLYSDYTFGV WNGDTLVPFA KAYSGLTDQE MKAVDAYVKK
NTRERFGPVR TVTPGLVFEI AFEGIQESPR HKSGIALRFP RIHRWRRDKS IESANTLEDL
QLLLEKYGK
//
