ID A0A1H6UT40_9MICO Unreviewed; 475 AA.
AC A0A1H6UT40;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Arginine:ornithine antiporter, APA family {ECO:0000313|EMBL:SEI91225.1};
GN ORFNames=SAMN05421637_0389 {ECO:0000313|EMBL:SEI91225.1};
OS Demequina mangrovi.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Demequinaceae;
OC Demequina.
OX NCBI_TaxID=1043493 {ECO:0000313|EMBL:SEI91225.1, ECO:0000313|Proteomes:UP000183315};
RN [1] {ECO:0000313|Proteomes:UP000183315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24868 {ECO:0000313|Proteomes:UP000183315};
RA Varghese N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2)
CC family. {ECO:0000256|ARBA:ARBA00008220}.
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DR EMBL; FNZI01000001; SEI91225.1; -; Genomic_DNA.
DR RefSeq; WP_042212562.1; NZ_FNZI01000001.1.
DR AlphaFoldDB; A0A1H6UT40; -.
DR STRING; 1043493.SAMN05421637_0389; -.
DR eggNOG; COG0531; Bacteria.
DR OrthoDB; 3185104at2; -.
DR Proteomes; UP000183315; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR004754; Amino_acid_antiprt.
DR NCBIfam; TIGR00905; 2A0302; 1.
DR PANTHER; PTHR42770; AMINO ACID TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR42770:SF4; ARGININE_ORNITHINE ANTIPORTER-RELATED; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
DR PRINTS; PR00173; EDTRNSPORT.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000183315};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 475 AA; 50431 MW; FB0E790D8D3BE50C CRC64;
MAGSPERAPV KLSLLTMTTM VVGTMVGAGV FTLPQRFAAA TGVSGALIAW TIAGAGTLTL
ALMFQALSNR KPHLDAGIYA YAKAGFGEYL GFFSAFGYWA TTCVGNVAFW VLIMSTLGGL
FPALGEGDTI LAVALSTAGL WGFYLLVRQG VREAAAINRI VTFAKLVPIL VFIVIALFYV
DPQVFADNMS GQGGEPLFDQ VKATMLVMVF VFLGVEGASV YSRHAKRRED VGRATVLGYL
SVFAIFASVT MVSYGIMPVA EMAELRQPSM AGVLEAAVGG WGSVFVSVGL IVSILGAYLA
WTMIAAELLF VAAKDGDMPR FLARQSSRDV PVAALLTTSW LTQGVLLVVL VSADAVNFMV
DLTSALSLIP FLFAAGYLLK IAALRDGYDE ARSRRRELAL GILTTAYVAF LLFAAGLTFV
LVSAIIYAPA SILFIMVRRE QGRRWFSPRE SIILAVSLAA AAVGAVGLAT GWLSI
//
