ID A0A1H6V4N3_9PSED Unreviewed; 364 AA.
AC A0A1H6V4N3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=SAMN03159495_1914 {ECO:0000313|EMBL:SEI99498.1};
OS Pseudomonas sp. NFR16.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1566248 {ECO:0000313|EMBL:SEI99498.1, ECO:0000313|Proteomes:UP000199219};
RN [1] {ECO:0000313|EMBL:SEI99498.1, ECO:0000313|Proteomes:UP000199219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NFR16 {ECO:0000313|EMBL:SEI99498.1,
RC ECO:0000313|Proteomes:UP000199219};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; FNYJ01000002; SEI99498.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6V4N3; -.
DR STRING; 1566248.SAMN03159495_1914; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000199219; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 27..359
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 364 AA; 40395 MW; 913A84575F031C02 CRC64;
MTAQVVSAQS SGQPACDTVL SEVRNHIGHI TLNRPQGLNA IDLDMVRQLQ DQLEAWARDE
KVYAVVLRGA GDKAFCAGGD IRSIYDSFKG GHTEHLDFFA EEYALDLTLH HYRKPVMALM
DGFVLGGGMG LAQGVDLRVV TERSRLAMPE VAIGYFPDVG GSYFLPRVPG ELGIYLGVTG
VQIQAADALY CGLADWCIDS ARLDELDRQL DLLKWSLTPL KDLQGVLAKL AVQQLPEPPL
EKLRPAIDHF FALPDIPSII EQLLQVNVID SHRWAVDTAN LMNTRSPLAM AVTLELLRRG
RHLPLETCFD LELHLDRQWF ERGDLIEGVR ALIVDKDKKP QWNPSSVQSL EGEHVASFFS
GHEA
//
