ID   A0A1H6WES8_9BACT        Unreviewed;       320 AA.
AC   A0A1H6WES8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=4-hydroxy-tetrahydrodipicolinate synthase {ECO:0000313|EMBL:SEJ12617.1};
GN   ORFNames=SAMN04487995_3351 {ECO:0000313|EMBL:SEJ12617.1};
OS   Dyadobacter koreensis.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC   Dyadobacter.
OX   NCBI_TaxID=408657 {ECO:0000313|EMBL:SEJ12617.1, ECO:0000313|Proteomes:UP000199532};
RN   [1] {ECO:0000313|EMBL:SEJ12617.1, ECO:0000313|Proteomes:UP000199532}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19938 {ECO:0000313|EMBL:SEJ12617.1,
RC   ECO:0000313|Proteomes:UP000199532};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
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DR   EMBL; FNXY01000005; SEJ12617.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H6WES8; -.
DR   STRING; 408657.SAMN04487995_3351; -.
DR   OrthoDB; 9796205at2; -.
DR   Proteomes; UP000199532; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199532}.
FT   ACT_SITE        144
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        172
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
SQ   SEQUENCE   320 AA;  35139 MW;  A88DEB95DDDE3CD7 CRC64;
     MTAITNSLPQ GFIPVMLTPF LETGEVDYAG LKTLTEFYLT TGAAGLFANC LSSEMFELSE
     DERISVTKAV VDQVAGRLPV VATGTFGGPI SDQAEFVKRI YGTGVQAAII ISGLIADESD
     SDEEFLKNAL ELISLTGDIP LGFYECPVPY KRLVPSNILE PLVATGRVVY HKDTCLDLAE
     VKQRIALADG QQFGLYDAYM VNAVASLKAG AAGLSCIQGN IYPELVVWIC KNFNNPERQE
     DVKKVQQFFI DSMDLVHTAY PIIAKYSLQK RGFPISLYTR REVGVLTPEL KTQMDNLLVE
     VEKIQADLGI PSNFTQYLVK
//