ID A0A1H6WIN8_9GAMM Unreviewed; 614 AA.
AC A0A1H6WIN8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=ATP-binding cassette, subfamily B, multidrug efflux pump {ECO:0000313|EMBL:SEJ16909.1};
GN ORFNames=SAMN04487997_2614 {ECO:0000313|EMBL:SEJ16909.1};
OS Frateuria terrea.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Rhodanobacteraceae; Frateuria.
OX NCBI_TaxID=529704 {ECO:0000313|EMBL:SEJ16909.1, ECO:0000313|Proteomes:UP000199420};
RN [1] {ECO:0000313|EMBL:SEJ16909.1, ECO:0000313|Proteomes:UP000199420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26515 {ECO:0000313|EMBL:SEJ16909.1,
RC ECO:0000313|Proteomes:UP000199420};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNYC01000005; SEJ16909.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6WIN8; -.
DR STRING; 529704.SAMN02927913_2591; -.
DR OrthoDB; 9806127at2; -.
DR Proteomes; UP000199420; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR PANTHER; PTHR24221:SF203; ATP-BINDING_PERMEASE FUSION ABC TRANSPORTER-RELATED; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SEJ16909.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199420};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..328
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 362..601
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 614 AA; 68001 MW; 845F79255F1A819D CRC64;
MLFRWFESLI DPFKEPADTM PPRPVGRFYL FYLRQVWPMF VAVLVVGFFV SIIEVSLFAF
IGRLVDMAKV AEGAAFFRQH GRELMWMAFV ALIARPVFNS LHDLLVNQAI VPNVTARIRW
QNHRYVIRQS LSFFQNDFAG RIANRIMQTG SSLRESAVQI VDAIWYVAIY TGSAIVMFAK
ADAWLAAPLV LWLLLYVATL AFFIPRTRQR SWKASEARSK LMGRIVDGYS NVLTLKLFAH
TRREEIYVAE ALHEQVDKTR AMTRQTTAMD ATITTLNGFL IVGTSGLALW LWSHGQVTVG
AIALSTGLVI RINNMSGWIM WVVNGIFENI GTVQDGMETI AQPRTVQDAP DAMPLAVTRG
DVRFQDIHFH YGKAGGVIAG LDLTVHAGEK IGLVGPSGAG KSTLVNVLLR LYDLEGGRIL
IDGQDIARVT QESLRSQIGV VTQDTSLLHR SIRDNLLYGR PDATEAQIAE AVRKARADEF
IPTLSDGEGR QGYDAYVGER GVKLSGGQRQ RIAIARVLLK DAPILVLDEA TSALDSEAEA
AIQESLDLLM QGKTVIAIAH RLSTIARMDR LVVLDRGRIV ESGTHAQLIA HGGLYARLWE
RQTGGFVAAE DALA
//
