ID A0A1H6WS96_9GAMM Unreviewed; 503 AA.
AC A0A1H6WS96;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Radical SAM superfamily enzyme YgiQ, UPF0313 family {ECO:0000313|EMBL:SEJ18084.1};
GN ORFNames=SAMN04487997_2651 {ECO:0000313|EMBL:SEJ18084.1};
OS Frateuria terrea.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Rhodanobacteraceae; Frateuria.
OX NCBI_TaxID=529704 {ECO:0000313|EMBL:SEJ18084.1, ECO:0000313|Proteomes:UP000199420};
RN [1] {ECO:0000313|EMBL:SEJ18084.1, ECO:0000313|Proteomes:UP000199420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26515 {ECO:0000313|EMBL:SEJ18084.1,
RC ECO:0000313|Proteomes:UP000199420};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; FNYC01000005; SEJ18084.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6WS96; -.
DR STRING; 529704.SAMN02927913_2628; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000199420; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000199420}.
FT DOMAIN 5..141
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 188..409
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 503 AA; 57038 MW; 9D5DFC18A275AB1D CRC64;
MTRPPRTLLI NPTIASRHSA RFPLPLLNLA AALDQHGQSR ILDGNIERDT VPEVLRALDH
ESFDAVGMTV MGGPHVPEAI KLSRAIREHS PGLPIIWGSY FPTLFTDAAL NAPYVDYAVR
GQGEETLVEL VCALTGQGPP LAAIAGLSWK DGDRIVHNPA RRFSRGNPPP LLPYEKLGDP
RKYLARTFLG QRTVAHQAAL GCRYHCTFCG VAAMFGGATA LPAAARLERE LGYLKHELGA
DSVQFFDHNF FDREAEMVPL LEVLARLELP WWCFARADAL VNLSEANWKL VRKSRLRMAY
IGAESPDGQM LREIRKGTRP DQTLQVAEVC RRHGVIPEFS FMVAPPTHTE EETEQTFEFI
RQLKRVNPAC EIVIYIYTPL PENAMHEKDR GRHRATPLID LHGAPVVFPS SPDEWAQPQW
VNYACHADAP WLDERLRRRI DDFVTVLRCR YPTVQDMRAP HWAKRTLSAM AAWRYRIGHY
DRPWELRLAN RFVQLRLPQV QGL
//
