ID A0A1H6Y342_9SPHN Unreviewed; 546 AA.
AC A0A1H6Y342;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=SAMN05428950_1011921 {ECO:0000313|EMBL:SEJ34856.1};
OS Sphingomonas sp. OV641.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1881068 {ECO:0000313|EMBL:SEJ34856.1, ECO:0000313|Proteomes:UP000199191};
RN [1] {ECO:0000313|Proteomes:UP000199191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV641 {ECO:0000313|Proteomes:UP000199191};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR EMBL; FNZB01000001; SEJ34856.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6Y342; -.
DR STRING; 1881068.SAMN05428950_1011921; -.
DR Proteomes; UP000199191; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:SEJ34856.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199191}.
FT DOMAIN 322..452
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 546 AA; 60552 MW; 4E81F19FBB9B804E CRC64;
MLASRSASAT PSVAPSMHAF AQLLDSLIYT RSRNAKLKLI GDYLRTTPDP DRGWAMAALT
GDLDIAGVKP AVIRGLIEER VDPVLYRMSR DFVGDSAETI ALLWPAPDLP DKPEPLSVAR
VIDRLMHLSR SEAPGALAQM LDVLDAEERF ALLKMATGAL RVGVSARLAK QALADAFGID
VDAVEEVWHG IEPPYASLFA WAEGRGEQPT ADNVPVFRPF MLAHPLEDLR VDLSDYAAEW
KWDGIRVQIV HLAGETRLYS RTGDDVTRAF PDVASAFAEH GVVDGELLVR GEAQGGTLEE
GGGAASFNAL QQRLGRKVVS PKMLDEAPAF VRLYDILFDG AEDLRALPWH ERRARLELFA
ERLNPDRFDV SALIEAEDFT ELEGIRAGAR DAAIEGVMLK RRDAPYVPGR RAGLWYKWKR
DPLTADCVMM YAQRGNGRRS SFYSDYTFGC WTEDGELLPV GKAYSGITDE ELRQLDKFVR
THTLNRFGPV REVEKTLVLE VAFDSIHASK RHKSGVAMRF PRISRIRTDK PAAEADTLAA
LQRLVT
//
