ID A0A1H6YZL7_9MICO Unreviewed; 1440 AA.
AC A0A1H6YZL7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:SEJ46668.1};
GN ORFNames=SAMN05421637_1886 {ECO:0000313|EMBL:SEJ46668.1};
OS Demequina mangrovi.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Demequinaceae;
OC Demequina.
OX NCBI_TaxID=1043493 {ECO:0000313|EMBL:SEJ46668.1, ECO:0000313|Proteomes:UP000183315};
RN [1] {ECO:0000313|Proteomes:UP000183315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24868 {ECO:0000313|Proteomes:UP000183315};
RA Varghese N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNZI01000004; SEJ46668.1; -; Genomic_DNA.
DR STRING; 1043493.SAMN05421637_1886; -.
DR eggNOG; COG1643; Bacteria.
DR Proteomes; UP000183315; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:SEJ46668.1};
KW Hydrolase {ECO:0000313|EMBL:SEJ46668.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000183315}.
FT DOMAIN 82..245
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 305..477
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1095..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1440 AA; 158738 MW; 04B400CFFBD8EF86 CRC64;
MREDWNNVPV SEDTRPRRNR RGRGGQRRDD ARRAGAPGQA SHRPQVSRRA LEAAAAKRAA
VEVPTIAYPE QLPVSARRDE IAAAIRDHQV VIVAGETGSG KTTQLPKICL ELGRGRAGQI
GHTQPRRIAA RSVADRIAEE LGTELGGLVG YQVRFTDQSS DSTLVKVMTD GILLAQIQRD
PDLLAYDTLI IDEAHERSLN IDFLLGYLTN LLPRRPDLKV IITSATIDSE RFARHFAAGG
PLPAREPVMD DADDADAGED RERDPREAPV VEVTGRTFPV EILYRPLEGA TKGDEKDLVT
GIVDACDELM TWGDGDILVF LSGEREIRDA ADGLEAHLGD RARNPRHPRR VEILPLYSRL
SAADQHRVFE RHTSRRIVLA TNVAETSLTV PGIHYVVDPG TARISRYSKA TKVQRLPIEP
ISQASARQRS GRAGRLADGI AIRLYSEEDF DARPPFTEPE ILRTSLASVL LQMISVGVVE
GPDDMARFPF VEPPDTRAIR DGVQLLSELG AISVREGRTS LTETGRKLAR LPIDPRQARM
IVEGARHGVA REVAVIAAAL SIQDPRERPT EKREEADLLH RRFADPSSDL LSYLNLWEHV
RERQHALSGN QFRRLCKSEY LNFLRVREWQ DLVQQLRDAA KAIDIEMAYR KPSPVDDAEG
TGALRHVWDD DGIHRSILAG LLSQVGAQDV LQLKASSFSH LKGEARAKEM RKARKRASNE
FIGARGIRFA INPGSPLSKK PPEFVMAAEL VETSRLWARD VARIDPAWAE ELAGDLAKRT
YSEPHWSSKR GAAMATEKVL LYGVPIVADR PVLWAKVNSE DARDLFIRHA LVQGEWTTHH
GFWRRNQRVL EEAAEVEARS RTRGVIADEE TLFAFYDARL PESIVSARHF DRWWQGARRE
DPELLTLTLD ELVPEHAAVD PSQFPERWPQ LDLELPLTYQ FEPGTAADGV TVHIPVGVLS
RVVEAGFDWL VPGMLPELVT ATVRALPKPV RRLLVPAPDA ARDIVAWLAA HVPAWVDVAR
AGDMAEPFRE AFTRAVRDLR DVEIPEDAWD GLDERLPGHL RMTFRVVEPG GRGQRILDES
HDLVHLQRRL APQAEAAVRT AVQRAADAAT RGKGRRDDAP AASPHPVASA PGGTPASSAR
PASAAVAEVD PLTAWPALDA LPDEVEGTVH GVVARGYPAI VEERKDGVRA ALRVLADATE
RDAAHARGVR RLLLAELALP VKRVTTRWTP AESLALGASP YRSTEALVDD LQLAAVTSLA
PEAGQVRDRV AYEALRTQVK DRLEDAVLDV ARQCAAALTA ARELDVAVRG ATSLALLATL
QELREQSAAL VGDGFVRTTP ADRLPHLARY LKAGAHRLEK AQADPQKDAQ LAWQIAQVTE
AYDTVRAAHA KGRMAPETAA ALDGVRWMIE ELRVSLFAQR LGTDGPVSEQ RIRKALAAIG
//
